Majör depresyonda uyku ataletinin değerlendirilmesi
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Dosyalar
Tarih
2010
Yazarlar
Dergi Başlığı
Dergi ISSN
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Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Majör depresyon toplumda oldukça yaygın görülen bir bozukluktur ve seyrinde bilişsel işlevler etkilenmektedir. Uyku ataleti uykudan uyandıktan hemen sonra olan bilişsel yavaşlama ile karakterize normal fizyolojik bir süreçtir. Bu çalışmada bilişsel işlevler de bozulmaya neden olan Majör Depresyon hastalarında bilişsel işlevlerde kısa süreli fizyolojik değişime neden olan uyku ataletinin değerlendirilmesi ve işlevsellikte olası kayıpların öngörülebilmesi için normal sağlıklı kontrollerle karşılaştırılması amaçlanmıştır. Bu amaçla DSM-IV'e göre Majör depresyon tanısı konan ve Hamilton Depresyon ölçeğinde 18 ve üstü puan alan 30 hasta ve 30 sağlıklı gönüllü çalışmaya alındı. Her iki guruba bazal ortalama değerler alınmak üzere VAS, iki dakikalık toplama işlemi testi, bilgisayarlı reaksiyon zamanı testi beş kez uygulandı. Uyku ataletinin süresini ve şiddetini objektif ve subjektif olarak değerlendirmek için sabah uyandıktan hemen sonra 1 saat içinde her 10 dakikada da bir ve 120. dakikada VAS, iki dakikalık toplama işlemi testi, reaksiyon zamanı testi uygulanarak uyanıklık ortalama değerleriyle karşılaştırıldı. Sonuç olarak Majör depresyon grubunda kontrol grubuna göre uyanıklık ortalama VAS, iki dakikalık toplama işlemi testi sonuçları düşük, Reaksiyon zamanları ise uzamış olarak bulunmuştur. Sabah yapılan ölçümlerin sonucuna göre Majör Depresyon hastalarının uyku ataleti süresi kontrollere göre anlamlı derecede uzamış ve şiddeti de artmıştır. Bu sonuçların gösterdiği kritik işlerde çalışan majör depresyonlu hastaların uyku ataletine bağlı hata yapma risklerinin artmış olduğudur.
Major depression is a common disease in a society and cognitive functions are affected during its course. Sleep inertia is a normal physiological process characterized with the cognitive deceleration shortly after waking from sleep. In this study, It has been aimed to evaluate the sleep inertia causes physicological changes in short-term on cognitive functions and to compare them with the normal healthy controls to predict the possible loses on functionary on the major depression patients who cause impairment in the cognitive functions. For this purpose, 30 patients who got 18 and +18 points in the Hamilton depression scale and 30 healthy people were chosen for this study. VAS,2-minute addition test, computerized reaction time test were applied 5 times to get the average rates in awakeness for the 2 groups. To evaluate the duration and the intensity of the sleeping inertia as an objective and subjective, awakeness average rates were compared by using VAS (after waking up, it was used in every 10 minutes in an hour and on the 120 th minute), 2-minute addition test and reaction time test As a result,major depression group's awakeness average VAS and 2-minute addition test results were lower than the control group?s and reaction times were found prolonged in the major depression group. Due to the results of the evaluations done in the morning, the duration of the major depression patients? sleep inertia were elongated and its intensity was increased significantly. These results show that the possibilities of making mistakes due to the sleep inertia were increased on the patients with major depression.
Major depression is a common disease in a society and cognitive functions are affected during its course. Sleep inertia is a normal physiological process characterized with the cognitive deceleration shortly after waking from sleep. In this study, It has been aimed to evaluate the sleep inertia causes physicological changes in short-term on cognitive functions and to compare them with the normal healthy controls to predict the possible loses on functionary on the major depression patients who cause impairment in the cognitive functions. For this purpose, 30 patients who got 18 and +18 points in the Hamilton depression scale and 30 healthy people were chosen for this study. VAS,2-minute addition test, computerized reaction time test were applied 5 times to get the average rates in awakeness for the 2 groups. To evaluate the duration and the intensity of the sleeping inertia as an objective and subjective, awakeness average rates were compared by using VAS (after waking up, it was used in every 10 minutes in an hour and on the 120 th minute), 2-minute addition test and reaction time test As a result,major depression group's awakeness average VAS and 2-minute addition test results were lower than the control group?s and reaction times were found prolonged in the major depression group. Due to the results of the evaluations done in the morning, the duration of the major depression patients? sleep inertia were elongated and its intensity was increased significantly. These results show that the possibilities of making mistakes due to the sleep inertia were increased on the patients with major depression.
Açıklama
Tıpta Uzmanlık
Anahtar Kelimeler
Psikiyatri, Psychiatry
