Carotid intima-media thickness:. a new marker of patients with uterine leiomyoma

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dc.authorwosidaksoy, yüksel/ABH-1304-2021
dc.authorwosidSAYIN, N. CENK/A-5801-2018
dc.contributor.authorAksoy, Yuksel
dc.contributor.authorSivri, Nasir
dc.contributor.authorKaraoz, Banu
dc.contributor.authorSayin, Cenk
dc.contributor.authorYetkin, Ertan
dc.date.accessioned2024-06-12T11:17:00Z
dc.date.available2024-06-12T11:17:00Z
dc.date.issued2014
dc.departmentTrakya Üniversitesien_US
dc.description.abstractObjective: To determine whether or not there are any significant differences in carotid intima-media thickness between patients with uterine leiomyoma and controls. Study Design: Patients whose ages were between 40 and 50 years, with body mass index <30 kg/m(2), and with a pathological diagnosis of uterine leiomyoma constituted the study group. Control subjects had no uterine leiomyoma proven by sonography. Demographic, clinical, and drug history data were collected. Right, left and mean carotid intima-media thickness measurements were obtained by ultrasonography. Results: Carotid intima-media thickness and serum high-density lipoprotein (HDL) levels were significantly different between the groups (p = 0.0001 and p = 0.001 respectively), being respectively higher and lower in the leiomyoma group than in controls. Stepwise binary logistic regression analysis revealed that uterine leiomyoma development ratio was 159.32 times higher when carotid intima-media thickness was over 0.61 mm (p = 0.0001). In patients with uterine leiomyoma, carotid intima-media thickness was significantly less in patients taking statins compared to those not on these drugs (p = 0.0001). Conclusion: The present study demonstrated a positive association between carotid intima-media thickness and the presence of uterine leiomyoma. Conversely, an inverse association was suggested between HDL and uterine leiomyoma. These findings suggest that women with uterine leiomyoma might have an increased risk of subclinical atherosclerosis. (C) 2014 Elsevier Ireland Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.ejogrb.2014.01.005
dc.identifier.endpage57en_US
dc.identifier.issn0301-2115
dc.identifier.issn1872-7654
dc.identifier.pmid24480112en_US
dc.identifier.scopus2-s2.0-84898057028en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage54en_US
dc.identifier.urihttps://doi.org/10.1016/j.ejogrb.2014.01.005
dc.identifier.urihttps://hdl.handle.net/20.500.14551/24536
dc.identifier.volume175en_US
dc.identifier.wosWOS:000335432000008en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofEuropean Journal Of Obstetrics & Gynecology And Reproductive Biologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectUterineen_US
dc.subjectLeiomyomasen_US
dc.subjectMyomasen_US
dc.subjectCardiovascularen_US
dc.subjectAtherosclerosisen_US
dc.subjectHypertensionen_US
dc.subjectStatinsen_US
dc.subjectSmooth-Muscle-Cellsen_US
dc.subjectRisk-Factorsen_US
dc.subjectHypertensionen_US
dc.subjectFibroidsen_US
dc.subjectDiseaseen_US
dc.subjectWomenen_US
dc.titleCarotid intima-media thickness:. a new marker of patients with uterine leiomyomaen_US
dc.typeArticleen_US

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