Screening for Hepatocellular Carcinoma: What Is Missing?

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dc.contributor.authorMehta, Neil J.
dc.contributor.authorCelik, Aygul Dogan
dc.contributor.authorPeters, Marion G.
dc.date.accessioned2024-06-12T11:17:51Z
dc.date.available2024-06-12T11:17:51Z
dc.date.issued2017
dc.departmentTrakya Üniversitesien_US
dc.description.abstractWhile there are guidelines from all major liver societies for the screening and management of hepatocellular carcinoma (HCC), many issues remain surrounding the actual practice of screening. This review discusses how to diagnose and screen HCC and more importantly, how well we diagnose and screen for HCC. Improved survival and outcomes after HCC diagnosis depend upon accurate diagnosis of cirrhosis and the timeliness of screening. With all oral direct-acting antivirals now widely available for hepatitis C, there are increasing numbers of patients who may be cured but are still at risk of HCC. Some uncontrolled studies suggest that direct-acting antiviral therapy may even increase the risk of HCC. Before we discuss expansion of who should be screened, we need physicians to realize how poorly we screen those patients who are already recommended for screening by guidelines.en_US
dc.identifier.doi10.1002/hep4.1014
dc.identifier.endpage22en_US
dc.identifier.issn2471-254X
dc.identifier.issue1en_US
dc.identifier.pmid29404430en_US
dc.identifier.scopus2-s2.0-85045835060en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage18en_US
dc.identifier.urihttps://doi.org/10.1002/hep4.1014
dc.identifier.urihttps://hdl.handle.net/20.500.14551/24869
dc.identifier.volume1en_US
dc.identifier.wosWOS:000453168400003en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherJohn Wiley & Sons Ltden_US
dc.relation.ispartofHepatology Communicationsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectClinical-Practice Guidelinesen_US
dc.subjectAlpha-Fetoproteinen_US
dc.subjectHepatitis-Cen_US
dc.subjectLiver-Transplantationen_US
dc.subjectAnnual Surveillanceen_US
dc.subjectCirrhotic-Patientsen_US
dc.subjectTumor Recurrenceen_US
dc.subjectLevelen_US
dc.subjectManagementen_US
dc.subjectMortalityen_US
dc.titleScreening for Hepatocellular Carcinoma: What Is Missing?en_US
dc.typeArticleen_US

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