Insulin resistance and lipid profile in women with polycystic appearing ovaries

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dc.authorwosidSAYIN, N. CENK/A-5801-2018
dc.contributor.authorSayin, NC
dc.contributor.authorGücer, F
dc.contributor.authorBalkanli-Kaplan, P
dc.contributor.authorYüce, MA
dc.contributor.authorYardim, T
dc.date.accessioned2024-06-12T11:12:34Z
dc.date.available2024-06-12T11:12:34Z
dc.date.issued2003
dc.departmentTrakya Üniversitesien_US
dc.description18th Annua Meeting of the European-Society-of-Human-Reproduction-and-Embryology -- JUN 30-JUL 03, 2002 -- VIENNA, AUSTRIAen_US
dc.description.abstractThe aim of this study was to investigate carbohydrate and lipid profiles in women with polycystic appearing ovaries (PCO) on ultrasound examination who did not fulfill the criteria for polycystic ovary syndrome (PCOS). We sonographically evaluated and biochemically diagnosed 35 patients with PCO, 31 women with PCOS and 23 healthy controls. We performed oral glucose tolerance tests (OGTT) and calculated the quantitative insulin sensitivity check index (QUICKI) and the homeostatic model assessment (HOMAIR) scores. Serum fasting insulin levels, 1-h insulin response, HOMAIR and QUICKI scores were significantly higher in the PCO and PCOS groups than in the controls. However, serum fasting glucose levels, fasting insulin levels, HOMAIR and QUICKI scores were similar in women with PCO and PCOS. In women with PCO, high-density lipoprotein (HDL) levels were higher, and very-low-density lipoprotein (VLDL) and triglyceride levels were lower compared with women with PCOS. Furthermore, insulin responses to OGTT, HOMAIR and QUICKI scores and lipid values correlated with serum androgen levels and body mass index (BMI) in PCO patients. In conclusion, women with PCO who do not fulfill the criteria for PCOS have abnormal insulin sensitivity and insulin resistance. The finding of similar insulin abnormalities in women with PCO to those in women with PCOS confirms that women with PCO have similar metabolic characteristics to those with PCOS.en_US
dc.description.sponsorshipEuropean Soc Human Reproduct & Embryolen_US
dc.identifier.doi10.1080/09513590312331290278
dc.identifier.endpage396en_US
dc.identifier.issn0951-3590
dc.identifier.issue5en_US
dc.identifier.pmid14710586en_US
dc.identifier.scopus2-s2.0-0242301686en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage387en_US
dc.identifier.urihttps://doi.org/10.1080/09513590312331290278
dc.identifier.urihttps://hdl.handle.net/20.500.14551/23214
dc.identifier.volume17en_US
dc.identifier.wosWOS:000186228600004en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherParthenon Publishing Groupen_US
dc.relation.ispartofGynecological Endocrinologyen_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPolycystic Ovary Syndromeen_US
dc.subjectInsulinen_US
dc.subjectLipiden_US
dc.subjectAndrogenen_US
dc.subjectCardiovascular-Diseaseen_US
dc.subjectHyperandrogenic Womenen_US
dc.subjectGlucose-Toleranceen_US
dc.subjectObese Patientsen_US
dc.subjectHealthy Womenen_US
dc.subjectHyperinsulinemiaen_US
dc.subjectRisken_US
dc.subjectSensitivityen_US
dc.subjectEndocrineen_US
dc.subjectDisturbancesen_US
dc.titleInsulin resistance and lipid profile in women with polycystic appearing ovariesen_US
dc.typeConference Objecten_US

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