Dexmedetomidine: an alternative for epidural anesthesia in tension-free vaginal-tape surgery

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dc.authorwosidÖzkan, Sezai/HJP-8894-2023
dc.contributor.authorTuran, Alparslan
dc.contributor.authorSen, Huseyin
dc.contributor.authorSizlan, Ali
dc.contributor.authorYanarates, Omer
dc.contributor.authorOzkan, Sezai
dc.contributor.authorKoyuncu, Onur
dc.contributor.authorDagli, Guner
dc.date.accessioned2024-06-12T10:59:23Z
dc.date.available2024-06-12T10:59:23Z
dc.date.issued2011
dc.departmentTrakya Üniversitesien_US
dc.description.abstractAnesthetic management of tension-free vaginal-tape (TVT) procedures is sometimes difficult to deal with, especially when surgeons request a cough test. Dexmedetomidine has unique sedative and analgesic properties while having minimal respiratory effects, making it suitable for perioperative use in monitored anesthesia care. We aimed to compare dexmedetomidine and epidural anesthesia in TVT patients. Forty-nine women [American Society of Anesthesiologists (ASA 1-3)] with genuine stress incontinence confirmed by preoperative bladder function studies were included in this double-blind, randomized study. The patients were randomly assigned to one of two groups: group D received 0.5 mu g/kg dexmedetomidine IV applied as bolus over 10 min and continued with 0.5 mu g/kg/h infusion, and local anesthesia (lidocaine 2% with epinephrine) performed by the surgeon. Group E received epidural anesthesia with 15 ml of 0.25% bupivacaine + 100 mu g fentanyl. Patients were monitored every 5 min for mean arterial pressure (MAP), heart rate (HR), peripheral oxygen saturation, respiratory rate, sedation, and intraoperative and postoperative pain. Ability to cough was also evaluated by the surgeon. There was no difference in ability to cough, and this was evaluated by the surgeon as adequate, and there was no difference in scores between groups. Significant decreases in MAP and HR were observed 10 min after the start of surgery in group D compared with group E, and they were significantly decreased until first and second postoperative hours, respectively (p < 0.05). None of the patients had respiratory rate decrease or apnea. Side effects encountered postoperatively were similar. Dexmedetomidine can be an alternative to epidural anesthesia in TVT procedure requiring cough test.en_US
dc.description.sponsorshipGulhane Military Medical Academy, Haydarpasa Training Hospital Uskudar, Istanbul, Turkeyen_US
dc.description.sponsorshipSupported by institutional and departmental sources at the Gulhane Military Medical Academy, Haydarpasa Training Hospital Uskudar, Istanbul, Turkey. None of the authors has a personal financial interest in this research.en_US
dc.identifier.doi10.1007/s00540-011-1113-8
dc.identifier.endpage391en_US
dc.identifier.issn0913-8668
dc.identifier.issue3en_US
dc.identifier.pmid21416311en_US
dc.identifier.scopus2-s2.0-79960048044en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage386en_US
dc.identifier.urihttps://doi.org/10.1007/s00540-011-1113-8
dc.identifier.urihttps://hdl.handle.net/20.500.14551/20425
dc.identifier.volume25en_US
dc.identifier.wosWOS:000291397000011en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringer Tokyoen_US
dc.relation.ispartofJournal Of Anesthesiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDexmedetomidineen_US
dc.subjectEpiduralen_US
dc.subjectTension-Free Vaginal Tapeen_US
dc.subjectFemale Urinary-Incontinenceen_US
dc.subjectStress-Incontinenceen_US
dc.subjectAlpha-2-Adrenoceptor Agonisten_US
dc.subjectUrethral Functionen_US
dc.subjectTvt Procedureen_US
dc.subjectSedationen_US
dc.subjectManagementen_US
dc.subjectAnalgesiaen_US
dc.subjectEfficacyen_US
dc.titleDexmedetomidine: an alternative for epidural anesthesia in tension-free vaginal-tape surgeryen_US
dc.typeArticleen_US

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