The impact of a single episode of remote ischemic preconditioning on myocardial injury after elective percutaneous coronary intervention

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dc.authoridTAYLAN, GOKAY/0000-0002-7015-4537
dc.authoridYILMAZTEPE, Mustafa/0000-0001-5328-5749
dc.authorwosidGURLERTOP, Hanefi Yekta/AAG-3036-2021
dc.authorwosidaksoy, yüksel/ABH-1304-2021
dc.authorwosidTAYLAN, GOKAY/HJZ-4693-2023
dc.authorwosidyilmaztepe, mustafa/AGE-8367-2022
dc.authorwosidAKTOZ, MERYEM/M-9023-2018
dc.contributor.authorYilmaztepe, Mustafa A.
dc.contributor.authorTaylan, Gokay
dc.contributor.authorAktoz, Meryem
dc.contributor.authorGurlertop, Hanefi Y.
dc.contributor.authorAksoy, Yuksel
dc.contributor.authorOzcelik, Fatih
dc.contributor.authorYalta, Kenan
dc.date.accessioned2024-06-12T11:12:17Z
dc.date.available2024-06-12T11:12:17Z
dc.date.issued2017
dc.departmentTrakya Üniversitesien_US
dc.description.abstractIntroduction: Myocardial injury after percutaneous coronary intervention (PCI) occurs in approximately 30% of procedures, and is related to worse prognosis. Effects of remote ischemic preconditioning (RIPC) on reperfusion injury have been investigated before, yielding conflicting results. Aim: To assess the impact of a single episode of RIPC on myocardial injury after elective PCI. Material and methods: One hundred and four patients undergoing elective PCI, with normal baseline cardiac troponin-I (cTn-I) values, were randomized to two groups. Two patients were excluded due to data loss, and 102 patients were analyzed. Five minutes of ischemic preconditioning was delivered just before the intervention to the preconditioning group, by inflating the blood pressure cuff up to 200 mm Hg on the non-dominant arm. Postprocedural 16th hour cTn-I, Delta cTn-I (difference between the 16th h and baseline cTn-I values) and the prevalence of type 4a myocardial infarction were compared between the two groups. Results: Median cTn-I values after the procedure were compared. 16th hour cTn-I was insignificantly lower in the preconditioning arm (0.026 mu g/l vs. 0.045 mu g/l, p = 0.186). The incidence of cTn-I elevation 5-fold above the upper reference limit (URL) (> 0.115 mu g/l) was lower in the preconditioning group, but it was also not significant (21.6% vs. 11.8%, p = 0.184). Conclusions: A single episode of RIPC before elective PCI demonstrated less troponin elevation but failed to show a significant effect.en_US
dc.identifier.doi10.5114/aic.2017.66185
dc.identifier.endpage46en_US
dc.identifier.issn1734-9338
dc.identifier.issn1897-4295
dc.identifier.issue1en_US
dc.identifier.pmid28344616en_US
dc.identifier.scopus2-s2.0-85016988197en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage39en_US
dc.identifier.urihttps://doi.org/10.5114/aic.2017.66185
dc.identifier.urihttps://hdl.handle.net/20.500.14551/23095
dc.identifier.volume13en_US
dc.identifier.wosWOS:000397101600007en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTermedia Publishing House Ltden_US
dc.relation.ispartofPostepy W Kardiologii Interwencyjnejen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPercutaneous Coronary Interventionen_US
dc.subjectRemote Ischemic Preconditioningen_US
dc.subjectMyocardial Injuryen_US
dc.subjectCrisp Stenten_US
dc.subjectProtectionen_US
dc.subjectTroponinen_US
dc.subjectInfarctionen_US
dc.subjectCycleen_US
dc.subjectMetaanalysisen_US
dc.subjectDefinitionen_US
dc.subjectValidationen_US
dc.subjectElevationen_US
dc.titleThe impact of a single episode of remote ischemic preconditioning on myocardial injury after elective percutaneous coronary interventionen_US
dc.typeArticleen_US

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