Delirium and extrapyramidal symptoms due to a lithium-olanzapine combination therapy: A case report
Küçük Resim Yok
Tarih
2005
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Korean Acad Medical Sciences
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
We report an elderly patient who developed severe delirium and extrapyramidal signs after initiation of lithium-olanzapine combination. On hospital admission, serum levels of lithium were found to be 3.0 mM/L which were far above toxic level. Immediate discontinuation of both drugs resulted in complete resolution of most of the symptoms except for perioral dyskinesia which persisted for three more months. We critically discussed the differential diagnosis of lithium intoxication and assessed confounding factors which induce delirium and extrapyramidal signs related with combination therapy of lithium and olanzapine.
Açıklama
Anahtar Kelimeler
Lithium, Drug Toxicity, Antipsychotic Agents, Olanzapine, Delirium, Neurologic Manifestations, Neuroleptic, Neuroleptic Malignant Syndrome, Atypical Antipsychotics, Neurotoxicity, Ketoacidosis, Parkinsonism, Intoxication, Sequelae, Patient
Kaynak
Journal Of Korean Medical Science
WoS Q Değeri
Q3
Scopus Q Değeri
Q1
Cilt
20
Sayı
4
