Recovery characteristics of desflurane, sevoflurane and halothane in children

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Tarih

2004

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Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

In our study, we aimed to assess recovery characteristics of desflurane compared with sevoflurane and halothane in children. After the local ethics committee approval, 90 ASA I-II status patients aged between 1-8 year scheduled for elective minor surgery, were included to the study. Patients were randomly divided into three groups each with 30 patients. Induction of anesthesia was done with sevoflurane 7% in O2 50 %+N2O 50%. Maintenance of anaesthesia was done with 1.3 MAC of desflurane in Group I, sevoflurane in Group II and halothane in Group III. Heart rate, systolic and diastolic arterial blood pressures, peripheral oxygen saturation and end-tidal carbon dioxide values were measured and recorded after the inhalation anaesthetics were switched off and during recovery periods. Recovery characteristics were assessed by Aldrete recovery score and pain was evaluated by pediatric objective pain scale. Time to first analgesic requirement and total dose of paracetamol required for the first 24 hours were recorded. Side effects encountered during induction and recovery periods were also noted. Aldrete recovery scores were 8.2±2.6 min, 12.7±2.8 min and 19.1±2.8 min in desflurane, sevoflurane and halothane groups respectively; and it was significantly shorter in desflurane group when compared with sevoflurane and halothane groups and it was significantly shorter in sevoflurane group when compared with halothane group (p<0.0005). However, hemodynamic parameters, oxygenation, postoperative pediatric objective pain scores, times to first analgesic requirement and total analgesic requirements for the first 24 hours and side effects were similar in three groups. As a result; desflurane could be an alternative to sevoflurane and halothane for the maintenance of anaesthesia in children, because of its faster recovery.

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Anahtar Kelimeler

Children; Desflurane; Halothane; Recovery; Sevoflurane, Desflurane; Halothane; Inhalation Anesthetic Agent; Nitrous Oxide; Oxygen; Paracetamol; Sevoflurane; Anesthesia Induction; Anesthetic Recovery; Article; Diastolic Blood Pressure; Elective Surgery; End Tidal Carbon Dioxide Tension; Heart Rate; Hemodynamics; Human; Major Clinical Study; Oxygen Saturation; Pediatric Anesthesia; Postoperative Pain; Preschool Child; School Child; Systolic Blood Pressure

Kaynak

Turk Anesteziyoloji ve Reanimasyon Dernegi Dergisi

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Scopus Q Değeri

N/A

Cilt

32

Sayı

3

Künye