Bacterial brain abscesses

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Date

2007

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Journal ISSN

Volume Title

Publisher

W B Saunders Co Ltd

Access Rights

info:eu-repo/semantics/closedAccess

Abstract

AIM: To assess the correlation between imaging findings [computed tomography (CT) or magnetic resonance imaging (MRI)] and neurological status before and after the treatment of bacterial brain abscesses. MATERIALS AND METHODS: CT and MRI images of 96 patients with brain abscesses were retrospectively evaluated in terms of the number, location and size of lesions, and the presence and extent of perilesional oedema and midline shift. An imaging severity index (ISI) based on these different radiological parameters was calculated. Initial Glasgow Coma Scale (GCS) scores and ISI were assessed and the prognostic value of these two indices was calculated. The Pearson correlation test, Mann-Whitney test, Chi-square test, receiver-operating characteristic (ROC) analysis, together with comparison of ROC analyses and Fisher's exact test were used. RESULTS: There was a negative correlation between 151 and the initial GCS values: ISI increased as the GCS score decreased, indicating an inverse relationship (r = -0.51, p < 0.0001). There was a significant difference between the ISI and GCS scores of patients with an adverse event compared with patients with good recovery. Outcome was significantly worse in patients with initial ISI over the calculated cut-off values of 8 points or GCS scores under the cut-off value of 13 points. CONCLUSION: ISI is a useful prognostic indicator for bacterial. brain abscess patients and correlates strongly with the patient outcome for all parameters studied. ISI score had a better prognostic value than GCS. (C) 2007 The Royal College of Radiologists. Published by Elsevier Ltd. All. rights reserved.

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Journal or Series

Clinical Radiology

WoS Q Value

Q3

Scopus Q Value

Q2

Volume

62

Issue

6

Citation