Pulmonary alveolar proteinosis in a patient with acute lymphoid leukemia regression after G-CSF therapy

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dc.authorwosidTurgut, Burhan/A-2517-2016
dc.contributor.authorPamuk, GE
dc.contributor.authorTurgut, B
dc.contributor.authorVural, Ö
dc.contributor.authorDemir, M
dc.contributor.authorHatipoglu, O
dc.contributor.authorÜnlü, E
dc.contributor.authorAltaner, S
dc.date.accessioned2024-06-12T11:13:07Z
dc.date.available2024-06-12T11:13:07Z
dc.date.issued2003
dc.departmentTrakya Üniversitesien_US
dc.description.abstractPulmonary alveolar proteinosis (PAP) is the intra-alveolar accumulation of periodic-acid schiff (PAS) positive material. PAP is one of the underrecognized causes of pulmonary infiltrates in patients with hematologic malignancies. Here, we present a patient with acute lymphoid leukemia (ALL) in first remission that developed fever and diffuse pulmonary infiltrates during the neutropenic stage of consolidation chemotherapy. The histopathologic examination of bronchoalveolar lavage (BAL) fluid and transbronchial biopsy specimen demonstrated the presence of PAS-positive eosinophilic material. Empirical antibiotherapy and granulocyte-colony stimulating factor (G-CSF) were given. After the correction of neutropenia with G-CSF, the patient's fever disappeared, acute phase reactants decreased, pulmonary infiltrates resolved. We present this case because it was the first patient in whom the correction of neutropenia with G-CSF was followed by resolution of PAP.en_US
dc.identifier.doi10.1080/1042819021000055093
dc.identifier.endpage874en_US
dc.identifier.issn1042-8194
dc.identifier.issue5en_US
dc.identifier.pmid12802928en_US
dc.identifier.scopus2-s2.0-0037402913en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage871en_US
dc.identifier.urihttps://doi.org/10.1080/1042819021000055093
dc.identifier.urihttps://hdl.handle.net/20.500.14551/23426
dc.identifier.volume44en_US
dc.identifier.wosWOS:000181057300020en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofLeukemia & Lymphomaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPulmonary Alveolar Proteinosisen_US
dc.subjectAcute Lymphoid Leukemiaen_US
dc.subjectGranulocyte-Colony Stimulating Factor (G-CSF)en_US
dc.subjectNeutropeniaen_US
dc.subjectChronic Myelogenous Leukemiaen_US
dc.subjectColony-Stimulating Factoren_US
dc.subjectAcute Myeloid-Leukemiaen_US
dc.subjectRespiratory-Failureen_US
dc.subjectDeficient Miceen_US
dc.subjectTransplantationen_US
dc.titlePulmonary alveolar proteinosis in a patient with acute lymphoid leukemia regression after G-CSF therapyen_US
dc.typeArticleen_US

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