Acromegaly
Küçük Resim Yok
Tarih
2007
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Growth hormone (GH) is necessary for normal linear growth. Excess secretion of GH induces gigantism in prepubertal children and acromegaly in adults. Acromegaly arises from GH-secreting pituitary adenomas. Syndromes of excessive secretion of GH or acromegaly are caused 95 % of the time by a pituitary adenoma of the somatotrophs. A few cases of ectopic GHRH-producing tumors, usually seen in the lung or pancreas, also have been described. Acromegaly is uncommon, with an incidence of 3-4 cases per million per year. Acromegaly is a severe disease often diagnosed late. Morbidity and mortality rates are high, in particular, because of associated cardiovascular, cerebrovascular, and respiratory disorders and malignancies.
Açıklama
Anahtar Kelimeler
Angiopeptin; Bromocriptine; Cabergoline; Dopamine Receptor Stimulating Agent; Growth Hormone; Octreotide; Pegvisomant; Somatostatin Derivative; Yttrium 90; Acromegaly; Article; Cardiovascular Disease; Cerebrovascular Disease; Clinical Feature; Disease Association; Gamma Radiation; Gigantism; Growth Hormone Release; Growth Hormone Secreting Adenoma; Growth Hormone Secreting Cell; Hormone Action; Human; Incidence; Malignant Neoplastic Disease; Morbidity; Mortality; Respiratory Tract Disease; Symptom
Kaynak
SENDROM
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
19
Sayı
6
