Antimicrobial evaluation of Tripleurospermum callosum (Boiss. & Heldr.) E. Hossain extracts using in vitro and in vivo Caenorhabditis elegans model against urinary system pathogens

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dc.authoridDemirci, Fatih/0000-0003-1497-3017
dc.authoridGoger, Gamze/0000-0003-2978-5385
dc.authoridGöger, Fatih/0000-0002-9665-0256
dc.authoridKöse, Yavuz Bülent/0000-0002-3060-7271
dc.authoridYuksel, Deniz/0000-0001-8696-9725
dc.authorwosidDemirci, Fatih/A-8295-2008
dc.authorwosidGoger, Gamze/JCE-6911-2023
dc.authorwosidGöger, Fatih/HTR-3454-2023
dc.authorwosidKöse, Yavuz Bülent/IZP-8734-2023
dc.contributor.authorGoger, Gamze
dc.contributor.authorYuksel, Deniz
dc.contributor.authorGoger, Fatih
dc.contributor.authorKose, Yavuz Bulent
dc.contributor.authorDemirci, Fatih
dc.date.accessioned2024-06-12T11:16:43Z
dc.date.available2024-06-12T11:16:43Z
dc.date.issued2024
dc.departmentTrakya Üniversitesien_US
dc.description.abstractTripleurospermum callosum (Boiss. & Heldr.) E. Hossain was recorded in Turkish ethnobotanical data for its use against urinary and respiratory system ailments. Infusion, decoction and 96% ethanol extracts of T. callosum aerial parts were prepared for in vitro antimicrobial activity against urinary system pathogens Escherichia coli ATCC 8739, Staphylococcus aureus ATCC 6538, Pseudomonas aeruginosa ATCC 9027, Klebsiella aerogenes ATCC 1348 and Candida albicans ATCC 10231. The non-toxic concentrations of extracts and in vivo antimicrobial assay were performed using C. elegans. The extracts were analysed by Liquid Chromatography Mass Spectrometry (LC-MS/MS) for phytochemical composition. The water extracts were non-toxic at between 5000 and 312 mu g/mL, while 96% ethanol extract at 312 mu g/mL for C. elegans. The infusion extract showed in vivo anti-infective effect 5000-312 mu g/mL against Gram-negative strains. The results indicate a potential role of plant extracts with relatively non-toxic and anti-infective effects against urinary system pathogens.en_US
dc.description.sponsorshipScientific and Technological Research Council of Tuerkiye (Tuebitak) [218S812]en_US
dc.description.sponsorshipThis work was financially supported by the Scientific and Technological Research Council of Tuerkiye (Tuebitak) with the Project number : 218S812. The authors thank the Sanovel Pharmaceutical Industry Istanbul, Tuerkiye, for providing standard antimicrobial agents. We also thank Prof. Dr. Volkan Aksoy for the English proofreading of the manuscript.en_US
dc.identifier.doi10.1080/09603123.2023.2221641
dc.identifier.endpage1478en_US
dc.identifier.issn0960-3123
dc.identifier.issn1369-1619
dc.identifier.issue3en_US
dc.identifier.pmid37288869en_US
dc.identifier.scopus2-s2.0-85161685806en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1466en_US
dc.identifier.urihttps://doi.org/10.1080/09603123.2023.2221641
dc.identifier.urihttps://hdl.handle.net/20.500.14551/24417
dc.identifier.volume34en_US
dc.identifier.wosWOS:001003262500001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofInternational Journal Of Environmental Health Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectTripleurospermum Callosumen_US
dc.subjectAntimicrobial Effecten_US
dc.subjectUrinary System Pathogensen_US
dc.subjectCaenorhabditis Elegansen_US
dc.subjectHplc-Dad-Esi/Msen_US
dc.subjectPhenolic-Compoundsen_US
dc.subjectMedicinal-Plantsen_US
dc.subjectEssential Oilen_US
dc.subjectLc-Msnen_US
dc.subjectIdentificationen_US
dc.subjectFlavonoidsen_US
dc.subjectAsteraceaeen_US
dc.subjectAciden_US
dc.subjectMatricariaen_US
dc.titleAntimicrobial evaluation of Tripleurospermum callosum (Boiss. & Heldr.) E. Hossain extracts using in vitro and in vivo Caenorhabditis elegans model against urinary system pathogensen_US
dc.typeArticleen_US

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