Frailty in patients with acute myeloid leukaemia, conceptual misapprehension of chronological age

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dc.authoridBaysal, Mehmet/0000-0001-7681-4623
dc.authoridUmit, Elif/0000-0001-5589-3000
dc.authorwosidBaysal, Mehmet/E-9111-2018
dc.contributor.authorUmit, E. G.
dc.contributor.authorBaysal, M.
dc.contributor.authorDemir, A. M.
dc.date.accessioned2024-06-12T11:00:00Z
dc.date.available2024-06-12T11:00:00Z
dc.date.issued2018
dc.departmentTrakya Üniversitesien_US
dc.description.abstractIn haematology practice, patients with acute myeloid leukaemia (AML) are generally assessed for frailty only if they are older and not able to tolerate intensive and remission targeted treatments. We aimed to focus on frailty in patients with AML, in all ages and aimed to evaluate its role and practicality in daily routine. Data of patients diagnosed and treated for AML between 2006 and 2016 are recorded and assessed for their survival predictivity. One hundred and ninety-seven patients were <65years of age and 175 were 65. Majority of the younger patients showed ECOG 2 performance (119, 60.4%). Combined with ECOG scale, G8 scale showed survival predictivity in younger patients as well as older patients. Nutritional status showed a strong predictivity in younger patients while remained insignificant in older patients. VES13 scale showed similar predictivity strength for survival in both age groups (p=.001). Young AML patients should be thoroughly evaluated as older patients. ECOG performance evaluation should be supported with further scales. Young patients with lower ECOG scores may be regarded as vulnerable with scales embracing dimensions such as nutrition, perception of disease, depression and cognition. Nutrition should be within the main goals of intensive treatment and is related with survival.en_US
dc.identifier.doi10.1111/ecc.12810
dc.identifier.issn0961-5423
dc.identifier.issn1365-2354
dc.identifier.issue2en_US
dc.identifier.pmid29337382en_US
dc.identifier.scopus2-s2.0-85040680080en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.urihttps://doi.org/10.1111/ecc.12810
dc.identifier.urihttps://hdl.handle.net/20.500.14551/20667
dc.identifier.volume27en_US
dc.identifier.wosWOS:000428321300047en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofEuropean Journal Of Cancer Careen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectECOGen_US
dc.subjectFrailtyen_US
dc.subjectLeukaemiaen_US
dc.subjectSupportive Careen_US
dc.subjectOlder-Adultsen_US
dc.subjectCancer-Patientsen_US
dc.subjectChemotherapy Toxicityen_US
dc.subjectAssessment Scaleen_US
dc.subjectMortalityen_US
dc.subjectPrevalenceen_US
dc.subjectMulticenteren_US
dc.subjectValidationen_US
dc.subjectDiagnosisen_US
dc.subjectDiseaseen_US
dc.titleFrailty in patients with acute myeloid leukaemia, conceptual misapprehension of chronological ageen_US
dc.typeArticleen_US

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