Evaluation of the prognostic value of plasma clearance rate of indocyanine green and Pitt bacteremia score in patients with sepsis

Basit Öğe Kaydı
dc.contributor.authorInal, Mehmet Turan
dc.contributor.authorMemis, Dilek
dc.contributor.authorSut, Necdet
dc.date.accessioned2024-06-12T10:54:09Z
dc.date.available2024-06-12T10:54:09Z
dc.date.issued2010
dc.departmentTrakya Üniversitesien_US
dc.description.abstractObjective: Sepsis is frequently seen in intensive care unit patients, representing an important cause of mortality. Prediction of prognosis in patients with sepsis is of particular importance. We investigated the relationship of plasma clearance rate of indocyanine green (ICG-PDR) and Pitt bacteremia score with prognosis in sepsis. Materials and methods: We retrospectively evaluated 100 patients whose ICG-PDR values were measured noninvasively with the LiMON system and Pitt bacteremia scores were determined within the first 24 hours of admission to intensive care unit. All the patients were diagnosed with sepsis before receiving intensive care. ICG-PDR values and Pitt bacteremia scores were compared between patients who died (n=48; mean age 62.4 16.5 years) or survived (n=52; mean age 60.8 +/- 18.2 years) during intensive care stay. Results: Compared to survivors, the mean ICG-PDR was significantly lower (21.1 +/- 5.4%/min vs. 13.9 +/- 6.4 %min; p<0.001) and the mean Pitt bacteremia score was significantly higher (4.9 +/- 2.0 vs. 10.2 +/- 1.7; p=0.000) in patents who died during intensive care treatment. In ROC analysis, the area under the curve was 0.819 for ICG-PDR, and 0.955 for Pitt bacteremia score. The optimal cut-off points for ICG-PDR and Pitt bacteremia score were 14.8%/min and 7, respectively. ICG-PDR and Pitt bacteremia score predicted mortality with a sensitivity of 75% and 97.9%, and specificity of 92.3% and 92.3%, respectively. Conclusion: Our findings show that both ICG-PDR and Pitt bacteremia score are effective markers in predicting survival of patients with sepsis and can be used in the evaluation of disease severity.en_US
dc.identifier.endpage5en_US
dc.identifier.issn2146-6416
dc.identifier.issn2147-267X
dc.identifier.issue1en_US
dc.identifier.startpage1en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/18948
dc.identifier.volume8en_US
dc.identifier.wosWOS:000219355700001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isotren_US
dc.publisherGalenos Yayinciliken_US
dc.relation.ispartofJournal Of The Turkish Society Of Intensive Care-Turk Yogun Bakm Dernegi Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBacteremia/Diagnosisen_US
dc.subjectCritical Illness/Mortalityen_US
dc.subjectHealth Status Indicatorsen_US
dc.subjectIndocyanine Green/Diagnostic Useen_US
dc.subjectIntensive Care Units/Mortalityen_US
dc.subjectMetabolic Clearance Rateen_US
dc.subjectPrognosisen_US
dc.subjectSensitivity And Specificityen_US
dc.subjectSepsis/Mortalityen_US
dc.titleEvaluation of the prognostic value of plasma clearance rate of indocyanine green and Pitt bacteremia score in patients with sepsisen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu