Right ventricular outflow tract function in chronic obstructive pulmonary disease

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dc.authoridÖzeke, Özcan/0000-0002-4770-8159
dc.authoridTufekcioglu, Omac/0000-0003-3478-9292
dc.authoridgölbaşı, zehra/0000-0002-5541-6252
dc.authorwosidGUL, Murat/L-5770-2015
dc.authorwosidGÜL, Murat/AAH-7852-2021
dc.authorwosidÖzeke, Özcan/N-1871-2015
dc.authorwosidÖzeke, Özcan/AAS-8730-2020
dc.authorwosidTufekcioglu, Omac/AAE-4660-2020
dc.authorwosidgölbaşı, zehra/HJI-1801-2023
dc.contributor.authorGeyik, B.
dc.contributor.authorTarakci, N.
dc.contributor.authorOzeke, O.
dc.contributor.authorErtan, C.
dc.contributor.authorGul, M.
dc.contributor.authorTopaloglu, S.
dc.contributor.authorAras, D.
dc.date.accessioned2024-06-12T11:13:43Z
dc.date.available2024-06-12T11:13:43Z
dc.date.issued2015
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBackground. It is clinically important to evaluate the severity of right ventricular (RV) overload in patients with chronic obstructive pulmonary disease (COPD), which is often associated with changes in the structure and the function of the right ventricle. Noninvasive and reliable assessment of RV function would be an essential determinant of RV load and a clinically useful factor for assessing cardiovascular risk in COPD patients. Objective. The aim of this study was to investigate the clinical application value of right ventricular outflow tract (RVOT) systolic function measured by transthoracic echocardiography in patients with COPD. Patients and methods. We prospectively investigated COPD male patients and compared them with healthy controls. In addition to RV conventional echocardiographic parameters, RVOT size and fractional shortening (RVOT-FS) parameters were also assessed. Results. Fifty-five COPD patients (all men; mean age, 62 +/- 9 years) participated in the study, and were compared with a control group consisting of 21male, healthy, nonsmoking subjects with a mean age of 58 +/- 11 years. The RVOT-FS was impaired in COPD patients than healthy controls (27.8 +/- 15.5 vs. 57.5 +/- 8.6, p< 0.001), and was correlated positively with tricuspid annular plane systolic excursion (TAPSE; r= 0.583, p< 0.001) and pulmonary acceleration time (r= 0.666, p< 0.001) and inversely with pulmonary artery systolic pressure (r= 0.605, p< 0.001) and functional capacity(r=-0.589, p< 0.001). There was a statistically significant difference in RVOT-FS among the COPD subgroups with regard to New York Heart Association functional classification (p< 0.001). Conclusion. The RVOT-FS is a noninvasive easily applicable measure of RV systolic function and is well correlated with functional capacity in COPD patients. Its combination with long-axis measurements via TAPSE and transtricuspid Doppler analysis may provide a comprehensive evaluation of the RV performance in COPD patients.en_US
dc.identifier.doi10.1007/s00059-013-3978-9
dc.identifier.endpage628en_US
dc.identifier.issn0340-9937
dc.identifier.issn1615-6692
dc.identifier.issue4en_US
dc.identifier.pmid24173376en_US
dc.identifier.scopus2-s2.0-84965090330en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage624en_US
dc.identifier.urihttps://doi.org/10.1007/s00059-013-3978-9
dc.identifier.urihttps://hdl.handle.net/20.500.14551/23661
dc.identifier.volume40en_US
dc.identifier.wosWOS:000356266000009en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherUrban & Vogelen_US
dc.relation.ispartofHerzen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectRight Ventricular Outflow Tracten_US
dc.subjectRight Ventricular Functionen_US
dc.subjectChronic Obstructive Pulmonary Diseaseen_US
dc.subjectTransthoracic Echocardiographyen_US
dc.subjectEvaluationen_US
dc.subjectEchocardiographic-Assessmenten_US
dc.subjectTricuspid Regurgitationen_US
dc.subjectMagnetic-Resonanceen_US
dc.subjectSystolic Functionen_US
dc.subjectLung-Diseaseen_US
dc.subjectRight Hearten_US
dc.subjectHypertensionen_US
dc.subjectQuantificationen_US
dc.subjectDysfunctionen_US
dc.subjectUltrasounden_US
dc.titleRight ventricular outflow tract function in chronic obstructive pulmonary diseaseen_US
dc.typeArticleen_US

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