Incidence, risk factors and severity of retinopathy of prematurity in Turkey (TR-ROP study): a prospective, multicentre study in 69 neonatal intensive care units

Basit Öğe Kaydı
dc.authorid0000-0002-1329-2167en_US
dc.contributor.authorBaş, Ahmet Yağmur
dc.contributor.authorAcunaş, Betül Ayşe
dc.date.accessioned2019-06-24T07:50:08Z
dc.date.available2019-06-24T07:50:08Z
dc.date.issued2018
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Anabilim Dalıen_US
dc.description.abstractBackground To evaluate the prevalence, risk factors and treatment of retinopathy of prematurity (ROP) in Turkey and to establish screening criteria for this condition. Methods A prospective cohort study (TR-ROP) was performed between 1 April 2016 and 30 April 2017 in 69 neonatal intensive care units (NICUs). Infants with a birth weight (BW)=1500 g or gestational age (GA)<= 32 weeks and those with a BW> 1500 g or GA> 32 weeks with an unstable clinical course were included in the study. Predictors for the development of ROP were determined by logistic regression analyses. Results The TR-ROP study included 6115 infants: 4964 (81%) with a GA <= 32 weeks and 1151 (19%) with a GA>32 weeks. Overall, 27% had any stage of ROP and 6.7% had severe ROP. A lower BW, smaller GA, total days on oxygen, late-onset sepsis, frequency of red blood cell transfusions and relative weight gain were identified as independent risk factors for severe ROP in infants with a BW=1500 g. Of all infants, 414 needed treatment and 395 (95.4%) of the treated infants had a BW <= 1500 g. Sixty-six (16%) of the treated infants did not fulfil the Early Treatment for Retinopathy of Prematurity requirements for treatment. Conclusions Screening of infants with a GA <= 34 weeks or a BW<1700 g appears to be appropriate in Turkey. Monitoring standards of neonatal care and conducting quality improvement projects across the country are recommended to improve neonatal outcomes in Turkish NICUs.en_US
dc.identifier.citationBas, A. Y., Demirel, N., Koc, E., Isik, D. U., Hirfanoglu, İ. M., & Tunc, T. (2018). Incidence, risk factors and severity of retinopathy of prematurity in Turkey (TR-ROP study): a prospective, multicentre study in 69 neonatal intensive care units. British Journal of Ophthalmology, 102(12), 1711-1716.en_US
dc.identifier.doi10.1136/bjophthalmol-2017-311789en_US
dc.identifier.endpage1716en_US
dc.identifier.issue12en_US
dc.identifier.pmid29519879en_US
dc.identifier.startpage1711en_US
dc.identifier.urihttps://doi.org/10.1136/bjophthalmol-2017-311789
dc.identifier.urihttps://hdl.handle.net/20.500.14551/4169
dc.identifier.volume102en_US
dc.identifier.wosWOS:000456552200020en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorAcunaş, Betül Ayşe
dc.language.isoenen_US
dc.publisherBMJ Publishing Groupen_US
dc.relation.ispartofBritish Journal of Ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz20240608_ID_Qen_US
dc.subjectFor-Gestational-Ageen_US
dc.subjectBlood-Transfusionen_US
dc.subjectWeight; Infantsen_US
dc.titleIncidence, risk factors and severity of retinopathy of prematurity in Turkey (TR-ROP study): a prospective, multicentre study in 69 neonatal intensive care unitsen_US
dc.typeArticleen_US

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