Fatal lactic acidosis due to metformine
Küçük Resim Yok
Tarih
2010
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
A 55 year-old male patient was admitted to emergency department. He ingested 50-60 tablets of 850 mg metformin for suicidal attempt. Blood glucose 352 mg/dL, ALT 52 IU/L, AST 39 IU/L, LDH 441 IU/L, lactate over 181 mg/dL, pH 7.29, pO2 44 mmHg, pCO2 39 mmHg, HCO3 18 mEq/L, oxygen saturation was 74%. Bicarbonate was given by intravenous push at a dose of 1 mEq/kg body weight and the patient was transferred to the intensive care unit. Haemofiltration was performed for lactic acidosis. As a result, haemofiltration should be initiated immediately in patients with acidosis associated with metformin. Thus mortality rates can be lessened. © Internet Scientific Publications, LLC., 1996 to 2010.
Açıklama
Anahtar Kelimeler
Emergency; Lactic Acidosis; Metformin, Alanine Aminotransferase; Aspartate Aminotransferase; Bicarbonate; Charcoal; Glipizide; Glucose; Hemoglobin; Lactate Dehydrogenase; Lactic Acid; Metformin; Rosiglitazone; Abdominal Pain; Adult; Case Report; Clinical Feature; Drug Overdose; Electrocardiogram; Glucose Blood Level; Heart Arrest; Hematocrit; Hemofiltration; Human; Hypotension; Lactic Acidosis; Letter; Leukocyte Count; Male; Nausea; Non Insulin Dependent Diabetes Mellitus; Oxygen Saturation; Ph; Respiratory Arrest; Resuscitation; Sinus Rhythm; Somnolence; Suicide Attempt
Kaynak
Internet Journal of Internal Medicine
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
8
Sayı
1
