Comparison of Tp-e interval, QTc interval and Tp-e/QTc ratios between non-diabetic and prediabetic population

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dc.contributor.authorArdahanlı, İsa
dc.contributor.authorÇelik, Mehmet
dc.date.accessioned2024-06-12T10:05:38Z
dc.date.available2024-06-12T10:05:38Z
dc.date.issued2020
dc.departmentTrakya Üniversitesien_US
dc.description.abstractAim: Increased blood glucose concentration and cardiac autonomic nerve dysfunction are associated with an increased risk of malignant ventricular arrhythmia. Tp-e interval, Tp-e/QT, and Tp-e/QTc are novel parameters used to assess ventricular arrhythmogenicity. This study aimed to compare these parameters with the healthy control group in prediabetics. Materials and Methods: The ECGs of 58 prediabetic patients (29 male, 59.74 ±13.25 years) were examined and matched with the ECGs of 59 healthy controls (28 male, 61.75 ± 12.66 years) that were matched with gender, age and body mass index. From the 12-lead ECG Tp-e and QT intervals were measured and by Bazett's formula QTc was calculated. Tp-e/QT and Tp-e/QTc proportions were also determined. Results: In prediabetic patients, the mean Tp-e interval was significantly longer than the control group (79.07 ± 8.17 vs 72.03 ± 9.77 ms, respectively; p 0.001). Also in prediabetic, Tp-e/QT and Tp-e/QTc were significantly higher than the controls (respectively 0.21 ± 0.25 vs 0.19 ± 0.03 and 0.19 ± 0.02 vs 0.17 ± 0.02; p 0.001). Other ECG parameters were similar in both groups. HbA1c levels and glucose levels were positively correlated with Tp-e / QT and Tp-e / QTc. Conclusion: Prediabetes increases the risk of ventricular arrhythmogenesis by increasing the transmural dispersion of repolarization. The addition of Tp-e interval and TP-e / QT measurements to the routine ECG evaluation of prediabetic patients can be used to predict arrhythmia risk.en_US
dc.identifier.doi10.5455/annalsmedres.2020.09.949
dc.identifier.endpage3122en_US
dc.identifier.issn2636-7688
dc.identifier.issue12en_US
dc.identifier.startpage3117en_US
dc.identifier.trdizinid427906en_US]
dc.identifier.urihttps://doi.org/10.5455/annalsmedres.2020.09.949
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/427906
dc.identifier.urihttps://hdl.handle.net/20.500.14551/13546
dc.identifier.volume27en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofAnnals of Medical Researchen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleComparison of Tp-e interval, QTc interval and Tp-e/QTc ratios between non-diabetic and prediabetic populationen_US
dc.typeArticleen_US

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