Docking Studies on the Effects of Some Bioactive Compounds from Pistacia atlantica Desf. against Main Protease SARS-CoV2

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dc.contributor.authorNadjat, Taıb
dc.contributor.authorTayeb, Sıtayeb
dc.contributor.authorBeşer, Necmi
dc.contributor.authorNadia, Aıssaouı
dc.date.accessioned2024-06-12T10:04:52Z
dc.date.available2024-06-12T10:04:52Z
dc.date.issued2021
dc.departmentTrakya Üniversitesien_US
dc.description.abstractNovel coronavirus which was named later as SARS-CoV2 appeared in Wuhan, China, in the end of December 2019. Actually, no precise drugs are existed and research concerning SARS-CoV2 treatment is deficient. SARS-CoV2 main protease (Mpro) was crystallized by Liu et al. (2020) and represented a crucial drug target. The present work aimed to evaluate some bioactive compounds from Pistacia atlantica as possible SARS-CoV2 Mpro inhibitors, based on molecular docking approach. Molecular docking was carried out using AutoDock Vina software. The results indicated that Beta-Eudesmol, Elemol, Verbenol, Pinocarvone, Myrtenal, Myrtenol and Trans-Carveol have a potential inhibitor activity of SARS-CoV2 Mpro. Nevertheless, further investigations are required to develop and optimize drug process to combat SARS-CoV2.en_US
dc.identifier.doi10.29329/ijiaar.2021.378.2
dc.identifier.endpage278en_US
dc.identifier.issn2602-4772
dc.identifier.issue3en_US
dc.identifier.startpage269en_US
dc.identifier.trdizinid493521en_US]
dc.identifier.urihttps://doi.org/10.29329/ijiaar.2021.378.2
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/493521
dc.identifier.urihttps://hdl.handle.net/20.500.14551/13100
dc.identifier.volume5en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofUluslararası tarım araştırmalarında yenilikçi yaklaşımlar dergisi (Online)en_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleDocking Studies on the Effects of Some Bioactive Compounds from Pistacia atlantica Desf. against Main Protease SARS-CoV2en_US
dc.typeArticleen_US

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