Investigation of the Pechmann reaction between 2,7-dihydroxynaphthalene and ethyl acetoacetate with different condensing agents. Synthesis of benzocoumarin and benzochromone systems and their bi- and bis-derivatives

Basit Öğe Kaydı
dc.authorscopusid7801447801
dc.authorscopusid6506475674
dc.contributor.authorKolancilar H.
dc.contributor.authorOyman Ü.
dc.date.accessioned2024-06-12T10:27:55Z
dc.date.available2024-06-12T10:27:55Z
dc.date.issued2003
dc.description.abstractAttempts were made to synthesise the benzocoumarin and benzochromone systems by Pechmann reaction. As an extension, it was also planned to make bi- and bis-derivatives of these compounds. 2,7-Dihydroxynaphthalene (DHN) and ethyl acetoacetate (EAA) were chosen as starting materials and 80% H 2SO4, PPA and HCIO4 were used as condensing agents. H2SO4 gave a benzochromone with a low yield together with isomeric benzocoumarins. PPA gave angular benzocoumarin and benzochromone but no linear benzocoumarin was obtained. When HCIO4 was employed the isomeric benzocoumarins were obtained with no indication of the formation of benzochromone ring. Attempts were also made to couple some of the compounds synthesised. Only one bi-benzocoumarin was obtained in one case. No angular benzocoumarin and angular benzochromone compounds gave the coupling reaction. Also, to obtain bis-derivatives, the Mannich reaction was applied.en_US
dc.identifier.endpage857en_US
dc.identifier.issn0019-4522
dc.identifier.issue9en_US
dc.identifier.scopus2-s2.0-1842812717en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage853en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/16982
dc.identifier.volume80en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherIndian Chemical Societyen_US
dc.relation.ispartofJournal of the Indian Chemical Societyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAcetic Acid Derivative; Acetoacetic Acid Ethyl Ester; Benzochromone; Benzocoumarin; Chlorine; Chromone Derivative; Coumarin Derivative; Hydrogen; Oxygen; Sulfuric Acid; Unclassified Drug; Article; Chemical Reaction; Drug Synthesis; Isomer; Polymerizationen_US
dc.titleInvestigation of the Pechmann reaction between 2,7-dihydroxynaphthalene and ethyl acetoacetate with different condensing agents. Synthesis of benzocoumarin and benzochromone systems and their bi- and bis-derivativesen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu