The Comparison of Polymorphisms in the Heat Shock Transcription Factor 1 Gene of Turkish Grey Cattle and Holstein Cattle

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dc.authorscopusid55567956000
dc.authorscopusid55885340800
dc.contributor.authorAtalay S.
dc.contributor.authorKök S.
dc.date.accessioned2024-06-12T10:27:54Z
dc.date.available2024-06-12T10:27:54Z
dc.date.issued2023
dc.description.abstractTurkish Grey cattle (B. taurus) are the only native cattle breed of Türkiye’s Thrace and Western Anatolia regions. They can spend the whole year as free herds, including the hottest and coldest months, and can survive, feed, and reproduce without any human intervention. Therefore, Turkish Grey cattle are of interest for genetic marker studies on heat stress tolerance. This study was aimed to identify genetic polymorphism in the DNA binding domain (DBD) encoding region of the heat shock transcription factor 1 (HSF1) gene in Holstein (n: 50) and Turkish Grey (n: 50) cattle. It was determined that the 121 amino acid long sequence encoded by the first three exons of the HSF1 gene was the same in Turkish Grey and Holstein cattle. Two intronic and one synonymous SNPs were identified in Turkish Grey (rs719296338, rs522980029, rs17880386) and one inronic SNP (rs17870386) in Holstein cattle by DNA sequencing. These SNPs were searched in the Bovine Genome Variation Database (BGVD). Interestingly, according to BGVD, rs522980029 was conserved in B. indicus but absent in B. taurus. Moreover, the rs719296338 locus is monomorphic in western European and Eurasian taurine but is polymorphic in East Asian taurines and B. indicus. The results support the view that B. indicus is genetic introgression into B. taurus cattle in Anatolia. This hybridization may have contributed to Turkish Grey cattle ability to adapt to harsh environmental conditions and heat stress. © 2023, Veteriner Fakultesi Dergisi. All rights reserved.en_US
dc.description.sponsorshipTekirdağ Namık Kemal Üniversitesi, TNKU: 22.353, NKUBAP.00en_US
dc.description.sponsorshipThis study was funded by the Scientific Research Projects Coordination Unit of Tekirdağ Namık Kemal University (Project number: NKUBAP.00.GA.22.353).en_US
dc.identifier.doi10.9775/kvfd.2023.29256
dc.identifier.endpage435en_US
dc.identifier.issn1300-6045
dc.identifier.issue5en_US
dc.identifier.scopus2-s2.0-85172002220en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage429en_US
dc.identifier.urihttps://doi.org/10.9775/kvfd.2023.29256
dc.identifier.urihttps://hdl.handle.net/20.500.14551/16966
dc.identifier.volume23en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherVeteriner Fakultesi Dergisien_US
dc.relation.ispartofKafkas Universitesi Veteriner Fakultesi Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectGenetic Introgression; Grey Cattle; Heat Stressen_US
dc.subjectHeat Shock Transcription Factor 1; Amino Acid Sequence; Article; Bovine; Dna Extraction; Dna Polymorphism; Dna Sequence; Dna Sequencing; Gene Amplification; Gene Frequency; Gene Sequence; Genetic Variability; Genotype; Holstein Cattle; Nonhuman; Polymerase Chain Reaction; Sanger Sequencing; Sequence Alignment; Sequence Analysis; Single Nucleotide Polymorphism; Taurine Cattleen_US
dc.titleThe Comparison of Polymorphisms in the Heat Shock Transcription Factor 1 Gene of Turkish Grey Cattle and Holstein Cattleen_US
dc.typeArticleen_US

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