Retinal ganglion cell complex and peripapillary retinal nerve fiber layer thicknesses following carotid endarterectomy
Küçük Resim Yok
Tarih
2019
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Purpose To examine changes in retinal ganglion cell complex (GCC) and peripapillary retinal nerve fiber layer (RNFL) thicknesses by optical coherence tomography (OCT) in contralateral and ipsilatateral eyes of carotid artery stenosis (CAS) patients before and after carotid endarterectomy (CEA). Methods Forty-two consecutive patients diagnosed with CAS (70-99% stenosis rate) who underwent CEA were included in this prospective cross-sectional study. The indication for CEA was based on the Asymptomatic Carotid Atherosclerosis Study. Doppler ultrasonography and computed tomography angiography were performed to calculate CAS. All the subjects underwent an ophthalmological examination, including best corrected visual acuity (BCVA), intraocular pressure (IOP) measurements, biomicroscopy, fundoscopy, and OCT before and after the surgery. ResultsThe mean preoperative intraocular pressure was 15.2 +/- 2.1mmHg in the ipsilateral eye and 15.8 +/- 2.7 in the contralateral eye. The mean post-operative intraocular pressure in the ipsilateral and contralateral eye was 18.6 +/- 3.0 and 19.3 +/- 3.8, respectively. The intraocular pressure was significantly higher in postoperative eyes (p=0.0001). There was a statistically significant decrease in peripapillary RNFL thickness in superior quadrants postoperatively in ipsilateral eyes. The retinal GCC layer thickness was not significantly different before and after CEA in ipsilateral and contralateral eyes. Conclusions Carotid endarterectomy results in thinning of the superior peripapillary RNFL thickness. To the best of our knowledge, this is the first study to examine peripapillary RNFL and GCC thicknesses before and after CEA.
Açıklama
Anahtar Kelimeler
Carotid Endarterectomy, Ganglion Cell Complex, Retinal Nerve Fiber Layer, Ischemic Optic Neuropathy, Endothelial Growth-Factor, Blood-Flow, Visual-Field, Neovascular Glaucoma, Reperfusion, Autoregulation, Circulation, Morphology, Symptoms
Kaynak
International Ophthalmology
WoS Q Değeri
Q4
Scopus Q Değeri
Q2
Cilt
39
Sayı
7
