Obesity Associated With Active, But Preserved Joints in Rheumatoid Arthritis: Results From our National Registry

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dc.authoridAyhan, Fikriye Figen/0000-0001-6906-991X
dc.authoridKaya, Taciser/0000-0002-8848-8420
dc.authoridAtaman, Sebnem/0000-0003-3570-3825
dc.authoridDogu, Beril/0000-0002-0690-4479
dc.authorwosidDoğu, Beril/AAU-3790-2020
dc.authorwosidAyhan, Fikriye Figen/O-4438-2014
dc.authorwosidKaya, Taciser/ABH-5966-2020
dc.authorwosidAtaman, Sebnem/AAA-2977-2020
dc.authorwosidPaker, Nurdan/JYP-3665-2024
dc.contributor.authorAyhan, Fikriye Figen
dc.contributor.authorAtaman, Sebnem
dc.contributor.authorRezvani, Aylin
dc.contributor.authorPaker, Nurdan
dc.contributor.authorTastekin, Nurettin
dc.contributor.authorKaya, Taciser
dc.contributor.authorBodur, Hatice
dc.date.accessioned2024-06-12T10:54:54Z
dc.date.available2024-06-12T10:54:54Z
dc.date.issued2016
dc.departmentTrakya Üniversitesien_US
dc.description.abstractObjectives: This study aims to investigate the prevalence of obesity in patients with rheumatoid arthritis (RA) and associations with disease outcomes. Patients and methods: The study population comprised of 1,038 patients with RA (198 males, 840 females; mean age 56.1 +/- 12.6 years; range 19 to 94 years) who had been included in National RA-Registry. RA disease activity measures, physical function, quality of life, joint destruction, laboratory tests, as well as pain, fatigue, general health, and patient and physician global health assessments on a visual analog scale were collected. Results: Our patients had established RA with mean disease duration of 10.2 +/- 8.8 years and moderate disease activity (disease activity score in 28 joints: mean 3.7 +/- 1.6). According to the body mass index (BMI), 70% of the patients were overweight (n= 362, 34.9%) or obese (n= 364, 35.1%). These patients had higher disease activity scores in 28 joints, visual analog scale-pain and visual analog scale-patient global scores, and higher levels of fasting blood glucose; however, they had lower radiographic scores than normal-BMI patients (p< 0.05). Regression analyses showed that the BMI was independently and inversely associated with disease activity scores in 28 joints and Sharp/van der Heijde scores after the adjustments for biologic and treatment-related factors (p< 0.05). Conclusion: Our findings indicate that obesity is more common in patients with RA than the general population. High disease activity and low radiographic damage were associated with high BMI in this National RA-Registry.en_US
dc.identifier.doi10.5606/ArchRheumatol.2016.5761
dc.identifier.endpage280en_US
dc.identifier.issn1309-0291
dc.identifier.issn2148-5046
dc.identifier.issue3en_US
dc.identifier.pmid29900954en_US
dc.identifier.scopus2-s2.0-84983242872en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage272en_US
dc.identifier.trdizinid203356en_US
dc.identifier.urihttps://doi.org/10.5606/ArchRheumatol.2016.5761
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/203356
dc.identifier.urihttps://hdl.handle.net/20.500.14551/19217
dc.identifier.volume31en_US
dc.identifier.wosWOS:000384910200011en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTurkish League Against Rheumatismen_US
dc.relation.ispartofArchives Of Rheumatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBody Mass Indexen_US
dc.subjectDisease Activityen_US
dc.subjectObesityen_US
dc.subjectRadiographic Damageen_US
dc.subjectRheumatoid Arthritisen_US
dc.subjectBody-Mass Indexen_US
dc.subjectDisease-Activityen_US
dc.subjectInsulin-Resistanceen_US
dc.subjectNecrosis-Factoren_US
dc.subjectAdipose-Tissueen_US
dc.subjectOverweighten_US
dc.subjectDamageen_US
dc.subjectLifeen_US
dc.titleObesity Associated With Active, But Preserved Joints in Rheumatoid Arthritis: Results From our National Registryen_US
dc.typeArticleen_US

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