The effectiveness of splenic autotransplantation

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dc.authoridKaragulle, Erdal/0000-0002-8522-4956
dc.authorwosidKaragulle, Erdal/C-6247-2017
dc.contributor.authorKaraguelle, Erdal
dc.contributor.authorHoscoskun, Zeki
dc.contributor.authorKutlu, Ali Kemal
dc.contributor.authorKaya, Meryem
dc.contributor.authorBaybar, Serkan
dc.date.accessioned2024-06-12T11:13:37Z
dc.date.available2024-06-12T11:13:37Z
dc.date.issued2007
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBACKGROUND The purpose of this study was to establish the effects of spleen autotransplantation on immunity and to examine the viability of autotransplanted spleen tissue. METHODS Three groups were assigned and following operations were performed in twenty New Zealand rabbits. 1st group: sham laparotomy, 2nd group: splenectomy and 3rd group: splenectomy and splenic autotransplantation. Scintigraphic methods, hematological-immunological tests and histopathological examination were used to evaluate the effects of splenic autotransplantation. RESULTS Histopathological findings showed that eight rabbits had splenic regrowth and two had necrosis of autotransplanted splenic tissue. Preoperative hematological and immunological findings compared with those at sixth week postoperatively. In group 3, postoperative immunoglobulin G, immunoglobulin M and interleukin-1 levels were significantly increased when compared with preoperative levels. Between all groups, postoperative leukocyte counts were found to be significantly higher in group 2 comparing with group 1. In group 2, postoperative platelet counts were significantly higher in comparison to group 1 and 3. No statistically significant difference was detected between the groups for immunoglobulin G, immunoglobulin M and interleukin-1 levels. CONCLUSION Conservative treatment is important in patients with splenic injury. However when splenectomy is indicated, splenic autotransplantation into the omentum pouch could be a reliable method for reconstruction of splenic functions and the viability of the implanted spleen tissue can be monitored by scintigraphy and laboratory examination.en_US
dc.identifier.endpage19en_US
dc.identifier.issn1306-696X
dc.identifier.issue1en_US
dc.identifier.pmid17310406en_US
dc.identifier.startpage13en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/23614
dc.identifier.volume13en_US
dc.identifier.wosWOS:000256734900002en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTurkish Assoc Trauma Emergency Surgeryen_US
dc.relation.ispartofUlusal Travma Ve Acil Cerrahi Dergisi-Turkish Journal Of Trauma & Emergency Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectReticuloendothelial Systemen_US
dc.subjectSpleen/Physiologyen_US
dc.subjectScintigraphyen_US
dc.subjectSpleen/Surgery/Transplantationen_US
dc.subjectSplenectomy/Adverse Effectsen_US
dc.subjectAuto-Transplantationen_US
dc.subjectSplenectomyen_US
dc.subjectTraumaen_US
dc.subjectSpleenen_US
dc.subjectTissueen_US
dc.subjectInfectionen_US
dc.subjectSplenosisen_US
dc.subjectSurvivalen_US
dc.subjectSepsisen_US
dc.titleThe effectiveness of splenic autotransplantationen_US
dc.typeArticleen_US

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