Effect of chewing gum on the management of chemotherapy-induced oral mucositis in children: Systematic review of experimental studies

dc.authoridsemerci, Remziye/0000-0003-1999-9179
dc.authorwosidsemerci, Remziye/ADA-6647-2022
dc.contributor.authorSemerci, Remziye
dc.contributor.authorKocaaslan, Esra Nur
dc.date.accessioned2024-06-12T10:56:13Z
dc.date.available2024-06-12T10:56:13Z
dc.date.issued2022
dc.departmentTrakya Üniversitesien_US
dc.description.abstractObjective It was aimed to systematically synthesise the available literature on examining the effect of chewing gum in the management/reduction of chemotherapy-induced oral mucositis in children. Methods The PRISMA was followed for the systematic review. All published studies obtained from the relevant databases were examined while the research question and inclusion and exclusion criteria were considered. The Joanna Briggs Institute (JBI) critical appraisal tools were used to evaluate the quality of the studies. Results A total of five studies met the inclusion criteria: three randomised controlled trials (RCT) and two quasi-experimental studies with a total of 461 paediatric oncology patients were included. Heterogeneity was found across all studies regarding the application of gum chewing and regarding the effectiveness of gum chewing. Two RTCs and one quasi-experimental study reported that gum chewing is not effective to reduce severe oral mucositis, but effective to reduce moderate and mild oral mucositis, and one RTC reported that gum chewing is not effective to reduce oral mucositis. Conclusion Experimental studies particularly randomised controlled trials using rigorous designs, consistent outcome measures, and larger sample sizes are required to determine the efficacy of chewing gum in reducing chemotherapy-induced oral mucositis in paediatric oncology patients. Study was registered in PROSPERO and number was CRD42022328916.en_US
dc.identifier.doi10.1111/ecc.13727
dc.identifier.issn0961-5423
dc.identifier.issn1365-2354
dc.identifier.issue6en_US
dc.identifier.pmid36239087en_US
dc.identifier.scopus2-s2.0-85139752469en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.urihttps://doi.org/10.1111/ecc.13727
dc.identifier.urihttps://hdl.handle.net/20.500.14551/19701
dc.identifier.volume31en_US
dc.identifier.wosWOS:000867582200001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofEuropean Journal Of Cancer Careen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectChemotherapyen_US
dc.subjectChewing Gumen_US
dc.subjectChildren With Canceren_US
dc.subjectOral Mucositisen_US
dc.subjectPaediatric Oncologyen_US
dc.subjectSystematic Reviewen_US
dc.subjectCanceren_US
dc.subjectTrialen_US
dc.titleEffect of chewing gum on the management of chemotherapy-induced oral mucositis in children: Systematic review of experimental studiesen_US
dc.typeReview Articleen_US

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