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Öğe Attitudes of patients with spondylarthritis or rheumatoid arthritis regarding biological treatment during COVID-19 pandemic: A multi-center, phone-based, cross-sectional study(Turkish League Against Rheumatism, 2021) Zateri, Coskun; Birtane, Murat; Aktas, Ilknur; Sarikaya, Selda; Rezvani, Aylin; Altan, Lale; Dursun, NigarObjectives: In this study, we aimed to investigate the medical treatment attitudes of patients with spondylarthritis or rheumatoid arthritis (RA) who were using biological drugs during the novel coronavirus-2019 (COVID-19) pandemic. Patients and methods: In this multi-center, cross-sectional study, a total of 277 patients (178 males, 99 females; median age: 45 years; range, 20 to 77 years) who were using biological disease-modifying anti-rheumatic drugs (bDMARDs) for rheumatic diseases and were reached by phone between June 1st, 2020 and June 30th, 2020 were included. Demographic characteristics, working status, type of the rheumatic disease, comorbidities, smoking habits, and type of the bDMARDs were recorded. Disease activity was evaluated using the Visual Analog Scale (VAS). The patients were asked whether they continued the treatment plan, as it was before or changed and, if changed, how they changed the plan and what happened after the change. Results: Of the patients, 229 had spondylarthritis and 48 had RA. A total of 36.1% of the patients were smokers, and the most common comorbidity was hypertension (17.3%). Totally, 5.8% of the patients had a history of contact with a COVID-19 positive person. Only three (1.1%) patients were diagnosed with COVID-19 infection and none of them died. Of the patients, 64.3% continued their treatment, while 35.7% adopted various changes. Most patients made the decision about the treatment plan on their own (n=160, 57.8%), while 38.3% of them consulted their physicians and 13.9% of them consulted any health staff. The only significant parameter for changing the drug course was receiving intravenous bDMARDs (by infusion at hospital) (p=0.001). These patients had also a higher disease activity as measured by VAS, compared to the patients receiving non-infusion therapy (p=0.021). As a result of these changes, severity of the symptoms increased in 91 (32.9%) patients. Disruption of regular biological treatment and prior infusion therapy more likely worsened the complaints (p<0.001 and p=0.024, respectively). Conclusion: Intravenous bDMARD therapy seems to be the main factor affecting the continuity of the treatment in the pandemic period. During the pandemic period, alternative treatment options should be considered other than infusion therapy not to interrupt the treatment of these patients.Öğe Comparison of the Short-Term Efficacy of Physical Therapy in Subacromial Impingement Syndrome Patients with Stage I and II Magnetic Resonance Imaging Findings(Turkish League Against Rheumatism, 2011) Hakguder, Aral; Tastekin, Nurettin; Birtane, Murat; Uzunca, Kaan; Zateri, Coskun; Sut, NecdetObjectives: In this study, we compared the efficacy of a combined physical therapy program between stage I and II subacromial impingement syndrome patients. Patients and methods: Forty-three patients with subacromial impingement syndrome assessed as stage I and II according to the magnetic resonance imaging (MRI) findings were included in the study. Constant's and University of California Los Angeles Shoulder Scales were used to evaluate pain and function. Pain levels at rest, during motion and while asleep were also scored by visual analog scale before treatment, after treatment and at one month after treatment. Improvements within and between the groups were assessed. A physical therapy program consisting of ultrasound, superficial heat therapy and transcutaneous electrical nerve stimulation modalities combined with an appropriate exercise program was applied to both groups during half monthly sessions. Results: The between-groups comparisons performed after treatment and during follow-up revealed no significant difference in terms of the outcome measures assessed. Conclusion: Stage II patients responded to the physical therapy program as well as patients with stage I MRI findings.Öğe Evaluation of the efficacy of therapeutic ultrasound on bone mineral density in postmenopausal period(Springer Heidelberg, 2008) Ozdemir, Ferda; Zateri, Coskun; Murat, SadiyeTherapeutic ultrasound is a frequently used modality in the practice of physical therapy. However, its effects on osteoporosis (OP) are not clear. We investigate the effect of therapeutic ultrasound on bone mineral density (BMD). We examined retrospectively 1,610 postmenopausal patients' data and we created two groups. The treatment group consisted of 36 patients who have been applied only the ultrasound treatment and the control group consisted of 38 patients who have never received any kind of physical treatment. Both of two groups have never received OP treatment. The mean values of BMD showed no significant difference between the treatment and control groups. Patients' BMD values, within the treatment group, were compared according to the treatment application region. There was no significant difference among groups. We determined that the ultrasound application has no effect on BMD. However, we consider that therapeutic ultrasound will help to decrease the skeletal system related complaints of the patients, improve their exercise capacity, and decrease the risk of osteoporosis.Öğe FREQUENCY OF RESTLESS LEGS SYNDROME IN RHEUMATOID ARTHRITIS(Oxford Univ Press, 2011) Zateri, Coskun; Kilinc, Serdar; Birtane, Murat; Tastekin, Nurettin[Abstract Not Available]Öğe Pain, Body Mass Index, and Bone Mineral Density in Patients with Postmenopausal and Senile Osteoporosis(Haworth Press Inc, 2009) Ozdemir, Ferda; Rodoplu, Meliha; Zateri, CoskunObjective: Osteoporosis [OP] itself does not cause pain and usually has no signs or symptoms. However, pain occurs when there is a fracture or a posture change due to OP. The purpose of this retrospective study was to explore the pain condition in patients with postmenopausal and senile OP. Methods: We studied symptoms of pain in 909 postmenopausal women between the ages of 33 and 89 years. The patients were retrospectively assessed in our outpatient service. Menopause age, duration of menopause, bone mineral density [BMD] values [gr/cm2], their reports of pain, duration of the pain experienced, and body mass index [BMI] were recorded. Results: We found 695 patients [76.45 percent] reported experiencing pain and 214 patients [23.54 percent] reported no pain. The duration of pain was 8.7 5.27 [minimum: 1, maximum: 26] years. We detected 82 cervical [11.79 percent], 77 dorsal [11.07 percent], 175 lumbar [25.17 percent], 183 knee [26.33 percent], and 177 general [25.46 percent] cases of pain. There was no significant difference in BMD between patients with and without pain [P 0.05]. The mean BMI of patients with pain were significantly higher than the mean BMIs of patients without pain. Among the patients who reported experiencing pain, the highest BMI values were in the knee pain group. Mean BMIs of the knee pain and dorsal pain groups were significantly higher than the mean BMIs of the painless group. Conclusion: OP commonly affects the spine and may cause debilitating pain. Pain can be either a warning sign of weakened bones and potential injury for women or a symptom of a spinal fracture. However, we did not find a significant association between a change in BMD and pain in postmenopausal and senile women. We detected a relationship between pain and BMI in the patients with knee, dorsal, and general pain.Öğe Probable osteosarcoma risk after prolonged teriparatide treatment: comment on the article by Saag et al(Wiley-Liss, 2010) Tastekin, Nurettin; Zateri, Coskun[Abstract Not Available]Öğe The reliability and validity of the Turkish version of the Fibromyalgia Participation Questionnaire(Aves, 2018) Altan, Lale; Celiker, Reyhan; Ercan, Ilker; Birtane, Murat; Akgun, Kenan; Zateri, Coskun; Tastekin, NurettinObjective: The objective of this study was to test the reliability and validity of the Turkish version of the Fibromyalgia Participation Questionnaire (FPQ). Methods: One hundred and eighty-four female patients with fibromyalgia syndrome were included in the study. All patients filled out the Turkish FPQ (FPQ-T) questionnaire, which was obtained by translation from German according to the guideline for the process of cross-cultural adaptation The patients filled out the revised Fibromyalgia Impact Questionnaire (FIQ) and reevaluated the FPQ-T two hours later. Internal consistency reliability of the FPQ-T was assessed by calculating the if item deleted using Cronbach's alpha and the item-total correction coefficient for each item of the questionnaire. The consistency of the subscales and the correlation of the test-retest values were assessed. The test-retest values were compared using the Wilcoxon test. Criterion validity was measured using FIQ scales by Spearman's rank correlation coefficient. Results: For internal reliability, Cronbach's alpha coefficient was calculated as 0.957 for nonworking patients and 0.958 for working patients. Cronbach's alpha values of 0.939, 0.871, and 0.914 were obtained for daily, social, and work life, respectively. Correlation coefficients were 0.888 for daily life, 0.859 for social life, and 0.901 overall in the nonworking group versus 0.896 the in working group. The comparison of scores obtained from test-retest measurements showed no significant difference except for Item 3. The correlation of the symptom severity score (SSS) and the FPQ-T was r=0.385 (p<0.001) and r=0.390 (p<0.001) for the nonworking and working subgroups, respectively. The evaluation of construct validity showed a significant correlation between the SSS and FPQ-T. Conclusion: The results of our study showed that the FPQ-T is reliable and valid for assessing participation and social functioning in fibromyalgia patients in Turkish society.Öğe Risk of Falls in Patients With Ankylosing Spondylitis(Lippincott Williams & Wilkins, 2015) Dursun, Nigar; Sarikaya, Selda; Ozdolap, Senay; Dursun, Erbil; Zateri, Coskun; Altan, Lale; Birtane, MuratBackground: Risk of vertebral fractures is increased in patients with ankylosing spondylitis (AS). The underlying mechanisms for the elevated fracture risk might be associated with bone and fall-related risks. The aims of this study were to evaluate the risk of falls and to determine the factors that increase the risk of falls in AS patients. Methods: Eighty-nine women, 217 men, a total of 306 AS patients with a mean age of 40.1 +/- 11.5 years from 9 different centers in Turkey were included in the study. Patients were questioned regarding history of falls within the last 1 year. Their demographics, disease characteristics including Bath AS Disease Activity Index, Bath AS Metrology Index (BASMI), Bath AS Functional Index (BASFI), and risk factors for falls were recorded. The Short Physical Performance Battery (SPPB) test was used for evaluation of static and dynamic balance. Erythrocyte sedimentation rate, C-reactive protein, and 25-hydroxyvitamin D levels were measured. Results: Forty of 306 patients reported at least 1 fall in the recent 1 year. The patients with history of falls had higher mean age and longer disease duration than did nonfallers (P = 0.001). In addition, these patients' BASMI and BASFI values were higher than those of nonfallers (P = 0.002; P = 0.000, respectively). We found that the patients with history of falls had lower SPPB scores (P = 0.000). We also found that the number of falls increased with longer disease duration and older age (R = 0.117 [P = 0.041] and R = 0.160 [P = 0.005]). Our results show that decreased SPPB scores were associated with increased number of falls (R = 0.183, P = 0.006). Statistically significant correlations were found between number of falls and AS-related lost job (R = 0.140, P = 0.014), fear of falling (R = 0.316, P = 0.000), hip involvement (R = 0.112, P = 0.05), BASMI (R = 0.234, P = 0.000), and BASFI (R = 0.244, P = 0.000). Conclusions: Assessment of pain, stiffness, fatigue, and lower-extremity involvement as well as asking for a history of falls will highlight those at high risk for further falls. In addition to the general exercise program adopted for all patients, we suggest that a balance rehabilitation program should be valuable for the patients with risk factors for fall. Exercise may improve fear of falling and BASFI and BASMI scores. However, further study is needed to investigate these hypotheses. We believe that clinicians should train and support the patients via reducing fear of falls and maintaining good posture and functional capacity.
