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Öğe Eccrine porocarcinoma: a case report and literature review(Kare Publ, 2007) Saynak, Mert; Kocak, Zafer; Altaner, Semsi; Ozen, Alaattin; Cosar Alas, Rusen; Yurut Caloglu, Vuslat; Uregen, BurcuEccrine porocarcinoma is a rare malignant sweat gland tumor. The lower extremity represents the most common tumor site for this entity. Surgical excision seems to be the best treatment choice. The surgical margins should be free of tumor, otherwise a local recurrence is most likely. Regional lymph node dissection should be performed if there is evidence of lymphadenopathy. Here, we present clinical and pathological findings of a 69 years old woman diagnosed with eccrine porocarcinoma arising from the skin of the trunk.Öğe MARJOLIN'S ULCER IN SCALP: CASE REPORT AND LITERATURE REVIEW(Kare Publ, 2005) Caloglu, Murat; Yurut Caloglu, Vuslat; Cosar Alas, Rusen; Ibis, Kamuran; Altaner, Semsi; Uzal, CemMarjolin's ulcer is a rare skin cancer that originates in areas of chronic wounds and scar tissues. It has more aggressive nature than other primary skin cancers. The exact mechanism of tumor development has not yet been identified. It could be seen on the skin of whole body surface. The most common histopathologic type of this malignancy is squamous cell carcinoma. It could develop in early and late period of time after trauma. Although surgery is still the main treatment, radiotherapy and chemotherapy could be other options in appropriate circumstances. In the present case report we described a patient who had lost her scalp in a work accident 25 years ago and developed skin cancer on scar tissue in late period, with a literature review.Öğe PROGNOSTIC FACTORS AND TREATMENT RESULTS IN LARYGEAL CARCINOMA: DEPARTMENT OF RADIATION ONCOLOGY OF TRAKYA UNIVERSITY MEDICAL SCHOLL EXPERIENCE(Kare Publ, 2005) Caloglu, Murat; Yurut Caloglu, Vuslat; Uzal, Cem; Karagol, Hakan; Tokatli, Fusun; Uygun, KazimPurpose: To review the Department of Radiation Oncology of Trakya University Medical School experience in the treatment of laryngeal carcinoma and to evaluate the different factors affecting locoregional control. Methods and Material: We reviewed the records of 78 consecutive patients were treated for laryngeal carcinoma between July 1999 and November 2004. There were 74 men and 4 women, with a median age of 58 years (range, 34-80 years). Forty-two patients had T4 lesions, and 20 had T3 lesions; 32 had NO, 15 had N1, 27 had N2, and 2 had Nx disease. Surgery was the primary treatment modality in 34 patients. Twenty-six patients had RT alone, or chemotherapy combined with RT. Eighteen patients applied with locoregional or distant recurrent disease and they were given salvage or palliative treatment. x2 statistics were employed to identify significant factors for LRC. Results: The median follow-up was 18 months (range, 4-54 months). Twelve patients relapsed, of which 9 (26.5 %) locoregional failures among 34 patients of postoperative radiotherapy group. Significant prognostic factors for locoregional recurrence on univariate analysis were performance status, and surgical margin. Nine of 26 (34.6 %) patients relapsed and all of them had locoregional failures in primary radiotherapy group. Significant prognostic factors for these patients were primary tumor site, overall stage, T stage, and N stage. Conclusion: Radiotherapy is effective in the treatment of laryngeal carcinoma. The identification of prognostic factors for locoregional recurrence could help to determine more effective treatment strategies.Öğe Recurrent Intracranial Meningeal Hemangiopericytoma with an Isolated Bone Metastasis: A Case Report and Literature Review(Kare Publ, 2017) Turkkan, Gorkem; Caloglu, Murat; Usta, Ufuk; Yurut Caloglu, Vuslat; Saygi, Haci Mehmet; Uzal, CemIntracranial meningeal hemangiopericytoma is a rare vascular tumor with a high rate of both local recurrence and the development of distant metastases. The aim of this report is to present the first case of recurrent meningeal hemangiopericytoma with an isolated femur metastasis and discuss the clinical features and treatment of this rare tumor. A 46-year-old woman was admitted with the complaint of sudden loss of consciousness and subsequently underwent an urgent craniotomy with total excision of the lesion. The diagnosis was meningeal hemangiopericytoma. The patient presented with a painful left hip 5 1/2 years after the initial surgery for the primary tumor. A lytic lesion, which was 4x4.5 cm in diameter, was seen on an X-ray of the proximal left femur. The patient underwent lesion removal surgery and pathological diagnosis was compatible with meningeal hemangiopericytoma. At 69th month, no progression has been observed in follow-up. Long-term follow-up is mandatory for meningeal hemangiopericytoma due to high recurrence rate many years after diagnosis. Further multi-institutional studies are strongly needed to understand the clinical behavior and treatment modalities of this rare disease.