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Öğe Brain atrophy and hypomyelination associated with iatrogenic cushing syndrome in an infant(Iranian Child Neurology Society, 2018) Dogan S.; Dogan M.S.; Tutunculer F.; Yapiciugurlar O.; Genchellac H.Prolonged use of topical corticosteroids, particularly in infants, albeit rare, may lead to Cushing syndrome. Central nervous system abnormalities including brain atrophy and delayed myelination on cranial magnetic resonance imaging has been reported in patients with corticosteroid treatment. We herein report a 5-month-old female infant referred to Department of Pediatric Endocrinology, Edirne, Turkey with brain atrophy and myelination delay that might be due to iatrogenic Cushing syndrome caused by topical corticosteroid use. © 2018, Iranian Child Neurology Society. All rights reserved.Öğe Insulin-induced oedema: a rare complication in a patient with newly diagnosed type 1 diabetes mellitus (a case report)(Zaslavsky Publishing House, 2020) Kostek H.Y.; Köroğlu N.; Çömlek F.Ö.; Dilek E.; Tutunculer F.Insulin-induced oedema is a rare complication of insulin therapy and occurs shortly after the initiation of intensive insulin therapy in patients with newly diagnosed type 1 diabetes mellitus (DM) or in patients with poorly controlled type 2 DM following the initiation of insulin therapy and also in underweight patients on large doses of insulin. It is characterized by the development of lower extremity oedema or less common generalized oedema after administration of insulin and resolves spontaneously within a few weeks. We report a case of a 9-year-old boy with newly diagnosed type 1 DM, who developed insulin oedema of lower extremities and scrotum within a few days after the initiation of insulin treatment. © 2020. The Authors.