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Öğe Comparison of dexmedetomidine with midazolam in premedication(Lippincott Williams & Wilkins, 2004) Kaya, G.; Turan, A.; Cetinaslan, O.; Pamukcu, Z.; Turan, N.[Abstract Not Available]Öğe Comparison of risk factors for warfarin-associated bleeding(Wiley-Blackwell, 2015) Ozgenel, M.; Umit, E.; Turan, N.; Demir, M.[Abstract Not Available]Öğe Comparison of the laryngeal mask (LMA™) and laryngeal tube (LT®) with the perilaryngeal airway (CobraPLA®) in brief paediatric surgical procedures(Australian Soc Anaesthetists, 2008) Kaya, G.; Koyuncu, O.; Turan, N.; Turan, A.We compared the laryngeal mask airway (LMA (TM)) and the laryngeal tube (LT (R)) with the perilaryngeal airway (CobraPLA (R), PLA) in anaesthetised, paralysed children having brief surgical procedures. After obtaining informed consent, 90 paediatric ASA Status 1 and 2 patients awaiting short surgical procedures were randomised to have their airways managed with an LMA, LT or PLA.,Anaesthesia was induced with sevofluarane (2.5 to 4%) and muscle paralysis with mivacurium (0.2 mg/kg intravenously). The number of insertion attempts, time taken to insert the device, haemodynamic responses to insertion (mean arterial blood pressure, heart rate, pulse oximetry and end-tidal CO), clinical performance and occurence of postoperative sore throat were recorded. When the airway device was removed, it was examined for visible blood. Patients and parents were asked about the occurrence of sore throat, dysphonia and dysphagia 24 hours postoperatively. Heart rate, mean arterial blood pressure, pulse oximetry and end tidal CO2 did not differ among the groups. Insertion times for the devices were similar (LMA: 19 +/- 11.seconds, LT: 21 +/- 12.seconds, PLA: 18 +/- 12 seconds), as were the rates of successful insertion at first attempt (LMA 66.7%; LT 70.0%; PLA 73.3%). The number and type of airway interventions to achieve at? affective airway were comparable. When the airways were removed, positive blood traces were noted on 20% of the LMAs, 20% of the PLAs and 10% of the LTs. Haemodynamic, ventilation and oxygenation variables throughout the surgery were similar with LMA, LT and PLA and there were no significant differences in insertion time or signs or symptoms of mucosal trauma when these devices were used in paralysed children.Öğe DETERMINING THE EFFICIENCY OF DIFFERENT PREOPERATIVE DIFFICULT INTUBATION TESTS ON PATIENTS UNDERGOING CAESAREAN SECTION(Lippincott Williams & Wilkins, 2016) Yildirim, I.; Inal, M. T.; Memis, D.; Turan, N.[Abstract Not Available]Öğe AN INVESTIGATION OF THE RELATIONSHIP BETWEEN THE eNOS GENE POLYMORPHISM AND DIAGNOSED MIGRAINE(Macedonian Acad Sciences Arts, 2014) Guler, S.; Gurkan, H.; Tozkir, H.; Turan, N.; Celik, Y.We investigated the phenotype-genotype association of the following endothelial nitric oxide synthase (eNOS) gene polymorphisms, rs743506, rs2070744, rs1799983, rs180079, rs3918226, rs207468799 and rs148554851, in patients suffering from migraine living in Edirne, Turkey. A total of 175 individuals, who had been diagnosed with migraine between April 2013 and December 2013, at the Neurology Department, Trakya University Medical Faculty, Edirne, Turkey, and 125 healthy controls were recruited. The above gene polymorphisms were analyzed from genomic DNA in both patient and control groups, using the pyro-sequencing method. The eNOS rs1799983 TT genotype frequency in migraine patients who had a headache duration of longer than 24 hours was statistically significantly higher than in patients who had migraine attacks that lasted under 24 hours (p = 0.047). In terms of the AGGTGGA haplotype, the severity of headache was statistically significant, and was found to be severe in 61.0% (p = 0.0001). Also in terms of the AGGTGGA haplotype, the duration of headache was statistically significant, and was >24 hours in 56.0% of patients (p = 0.008). In our study, there was no significant genotypephenotype relationship between eNOS rs743506, rs2070744, rs1799983, rs180079, rs3918226, rs207468799 and rs148554851 gene polymorphisms and migraine patients with and without aura living in Edirne, Turkey. The AGGTGGA haplotype constitutes a risk in terms of the severity and the duration of headaches in patients with migraine. This risk is significantly higher in patients with migraine with aura than patients with migraine without aura.Öğe Postmenopozal kadınlarda serum sitokin, osteokalsin, intakt PTH değerleri ile kemik mineral yoğunluğunun ilişkisi(2002) Kokino, S.; Turan, N.; Yıldız, M.Bu çalışma postmenopozal dönemdeki 108 kadın olgunun kemik mineral yoğunluğu (KMY) ile serum sitokin, osteokalsin ve intakt parathormon değerlerini karşılaştırmak üzere planlandı. Randomize seçilen 108 postmenopozal kadın olgu KMY ve medikal tedavisine göre 3 gruba ayrıldı. İlk grup 18 osteoporozu olmayan ortalama yaşı 52.94 ± 4.90 yıl ve ortalama postmenopoz süresi 6.5 ±4.76 yıl olan postmenopozal dönemdeki kadını kapsıyordu. İkinci grup medikal tedavi almayan, postmenopozal dönemde osteoporozu tesbit edilen, ortalama yaşı 53.60 ± 8.84 yıl ve ortalama postmenopoz süresi 9,73±6.75 yıl olan 15 kadından oluşuyordu. Üçüncü grup tedavi altında bulunan, ortalama yaşı 58.52±8.51 yıl ve ortalama postmenopoz süresi 13.20±8.41 yıl olan 75 osteoporozlu kadındı. Femur Wards üçgeni, torakanter ve lomber omurga kemik mineral yoğunluğu t skoru dual foton X ışını absorbsiometri (DEXA) kullanılarak ölçüldü. Serum kalsiyum, fosfor, C-reaktifprotein, eritrosit sedimentasyon hızı, sitokinler (interlökin-1, IL-1, interlökin-2, IL-2, interlökin:6, IL-6, interlökin-8, IL-8, tümör nekroze edici faktör alpha TNF-oc), osteokalsin, intakt paratiroid hormon düzeyleri tesbit edildi. Tüm olgularda lomber omurga, femur torakanter ve Wards üçgeni t skorları ile sitokin düzeyleri arasında anlamlı korelasyon bulunmadı. Diğer taraftan gruplar arasında yaş, tedavi süresi, lomber omurga, torakanter, Wards üçgeni t skorları ve postmenopoz süresi arasında anlamlı farklılık bulunur-ken, İL-1, İL-2, İL-6, İL-8, TNF-a , osteokalsin, intakt parathormon arasında yoktu. Sonuç olarak, özellikle erken postmenopozal dönemde sitokinlerin serum seviyelerinden çok kemik mikroçevresindeki düzeylerinin KMY ile korele olabileceğini düşünmekteyiz. Serum İL-6 düzeyi erken postmenopozal dönemde osteoporoz tedavi etkinliğinin takibinde yararlı olabilir.Öğe The Prevalence of Essential Tremor (ET) in Edirne and Its Districts Concomitant Comorbid Conditions(Wiley, 2020) Guler, S.; Caylan, A.; Turan, N.[Abstract Not Available]Öğe THE PREVALENCE OF ESSENTIAL TREMOR IN EDIRNE AND ITS COUNTIES ACCOMPANIED COMORBID CONDITIONS(Elsevier Sci Ltd, 2020) Guler, S.; Caylan, A.; Turan, N.; Dagdeviren, N.[Abstract Not Available]Öğe The Prevalence of Restless Legs Syndrome in Edirne and its districts: concomitant comorbid conditions and secondary complications(Wiley, 2017) Guler, S.; Caylan, A.; Turan, N.; Dagdeviren, N.; Celik, Y.[Abstract Not Available]Öğe RADIATION-INDUCED CHRONIC-OXIDATIVE RENAL DAMAGE CAN BE REDUCED BY AMIFOSTINE(Elsevier Ireland Ltd, 2011) Rusen, C.; Yurut-Caloglu, V.; Eskiocak, S.; Ozen, A.; Ibis, K.; Turan, N.; Denizli, B.[Abstract Not Available]Öğe Turkish version of the Johns Hopkins restless legs syndrome quality of life questionnaire (RLS- QoL): Validity and reliability study(Elsevier Science Bv, 2017) Guler, S.; Turan, N.[Abstract Not Available]Öğe Turkish version of the Johns Hopkins restless legs syndrome quality of life questionnaire (RLS-QOL): Validity and reliability study [Meeting Abstract](Elsevier, 2019) Guler, S.; Turan, N.[Abstract Not Available]Öğe The use of esmolol and magnesium to prevent haemodynamic responses to extubation after coronary artery grafting(Lippincott Williams & Wilkins, 2007) Arar, C.; Colak, A.; Alagol, A.; Uzer, S. S.; Ege, T.; Turan, N.; Duran, E.Background and Objective: The haemodynamic responses during extubation can cause complications after openheart surgery. In this study, we aimed to examine the effect of esmolol and magnesium before extubation on these haemodynamic responses. Methods: Following the approval of local Ethics Committee, 120 patients having coronary artery bypass grafting with extubation in the intensive care unit were included in the study. Patients were allocated to receive esmolol 1 mg kg(-1) (group 1, n = 40), magnesium 30 mg kg(-1) (Group 11, n = 40) or normal saline (Group 111, n = 40). Study medication was administered as a 20-min infusion in a volume of 20 mL. Patients were extubated just after termination of the infusion. Heart rate, blood pressure and central venous pressure were recorded prior to drug administration, before extubation, during extubation and I min after extubation. Results: Heart rate was lower in Group I than in Groups 11 (P < 0.05) and III (P < 0.001) and lower in Group 11 than in Group III (P < 0.05) during extubation. It was also lower in Group I than in Group III (P < 0.05) after extubation. Systolic blood pressure was lower in Group I than in Groups 11 and III (P < 0.001) during extubation. Diastolic blood pressure was higher in Group III than in Groups I and 11 during extubation (P < 0.001) and after extubation (P < 0.05). Mean arterial pressure was lower in Group I than in Groups 11 and III (P < 0.001) during extubation, lower in Group III than in Group III (P < 0.05) during extubation and lower in Group I than in Group III (P < 0.05) after extubation. Conclusion: We found that using esmolol before extubation following coronary artery bypass graft surgery prevents undesirable haemodynamic responses while magnesium reduces undesirable haemodynamic responses but does not prevent them.Öğe VALIDATION OF THE PARKINSON FATIGUE SCALE IN TURKISH PARKINSON'S DISEASE PATIENTS(Elsevier Sci Ltd, 2020) Guler, S.; Turan, N.[Abstract Not Available]Öğe Validation Turkish version of the simple screening tool for early diagnosis of advanced Parkinson's disease in daily practice: the CDEPA questionnaire(Wiley, 2020) Guler, S.; Turan, N.[Abstract Not Available]Öğe Validation Turkish version of the simple screening vehicle for early diagnosis of advanced Parkinson's disease in daily practice: The CDEPA questionnaire(Elsevier, 2019) Guler, S.; Turan, N.[Abstract Not Available]
