Yazar "Taylan, Gokay" seçeneğine göre listele
Listeleniyor 1 - 20 / 55
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Accessory mitral valve tissue: An overview of clinical and practical implications(Aves, 2021) Yalta, Kenan; Yetkin, Ertan; Yalta, Tulin; Taylan, Gokay[Abstract Not Available]Öğe Ace gene polymorphisms are ineffective on contrast induced nephropathy(Elsevier, 2022) Kilic, Ilhan; Palabiyik, Orkide; Taylan, Gokay; Sipahi, Tammam; Ustundag, SedatBackground: The renin-angiotensin system regulates the haemodynamics. ACE gene polymorphisms are known to influence serum angiotensin converting enzyme level. Contrast nephropathy develops after exposure to intravascular contrast media that influence vascular hemodynamics. ACE gene polymorpisms may have an enhancing role in contrast media related renal injury. The aim of the study: The aim of this study was to investigate the impact of ACE insertion/deletion (I/D) polymorphism in contrast-induced nephropathy (CIN) development. Methods: 194 patients with chronic kidney disease that were administered iodinated contrast media were examined. Patients were monitored for at least 7 days for CIN development after parenteral contrast exposure. Control and patient groups were divided in terms of CIN development status. Polymerase chain reaction was performed for the genotyping of the ACE gene polymorphism from DNAs that were isolated from peripheral blood of the patients. Results: 83 patients with CIN (34 women, 49 men) and 111 control patients without CIN (43 women, 68 men) were enrolled. Gender was not statistically different between the two groups (p = 0.75). The average age of the CIN group (71) was greater than that of the control group (68). No association was detected between ACE gene polymorphism (II, ID AND DD genotypes) and CIN in both patients and controls. Conclusion: ACE gene polymorphisms does not influence contrast induced nephropathy development.Öğe Acute effect of outflow tract premature ventricular complex ablation on QT dispersion, Tp-e interval and Tp-e/QT ratio(Taylor & Francis Ltd, 2021) Uslu, Abdulkadir; Kup, Ayhan; Gulsen, Kamil; Demir, Serdar; Kanar, Batur Gonenc; Taylan, Gokay; Sari, MunevverBackground: There is limited data regarding the effect of idiopathic premature ventricular complexes (PVC) on myocardial repolarisation. Most of PVC's originate from right and left ventricular outflow tracts (RVOT and LVOT). Aim: The aim of this study is to evaluate the acute effect of outflow tract PVC ablation on electrocardiographic repolarisation markers. Methods: A total of 180 patients (49.2 +/- 13.6 years, 74 male) without any exclusion criteria who had undergone outflow tract PVC ablation between 1 January 2015 and 1 November 2018 constituted our study population. Electrocardiographic recordings that had been obtained before and after ablation procedure on the same day were retrospectively evaluated for the QTc dispersion, Tp-e interval, Tp-e/QT ratio and Tp-e/QTc ratio. Significance of difference between pre- and postablation values was tested. Results: There was no significant difference regarding QTc dispersion between pre- and post-ablation state (36.5 +/- 20.9 vs. 35.3 +/- 16.4 ms, p: NS). However, Tp-e and Tp-e/QT values in all lateral precordial derivations were observed to decrease significantly after PVC ablation (in the respective order on derivation V5: 104.0 +/- 21.6 ms vs. 91.1 +/- 14.8 ms, pvs. 0.23 +/- 0.04, p<.001). Conclusions: Based on these observations, it may be suggested that frequent outflow tract PVC's increase transmural dispersion of repolarisation and this effect is attenuated by catheter ablation in the acute phase. Results of further prospective studies are required for evaluation of the long term effects of PVC ablation on myocardial repolarisation.Öğe The assessment of coronary microvascular dysfunction: An integral part of risk-stratification in Takotsubo cardiomyopathy(Elsevier Espana Slu, 2020) Yalta, Kenan; Gurdogan, Muhammet; Taylan, Gokay[Abstract Not Available]Öğe Association between Ascending Aorta Dilatation and Serum ?-Glutamyltransferase Levels(Elsevier Science Inc, 2013) Geyik, Bilal; Kaynak, Cagdas; Ozdemir, Ozcan; Yilmaz, Aykut; Yilmaztepe, Mustafa; Taylan, Gokay; Ozyamac, Ibrahim[Abstract Not Available]Öğe Association between Development of the Coronary Collateral Arteries and Epicardial Adipose Tissue Thickness(Elsevier Science Inc, 2013) Geyik, Bilal; Ozkalayci, Flora; Ozdemir, Ozcan; Kaynak, Cagdas; Yilmaztepe, Mustafa; Ozturk, Selcuk; Taylan, Gokay[Abstract Not Available]Öğe Association of Angiotensin II Type 1 Receptor A1166C Gene Polymorphisms with Coronary Artery Disease in Thrace Region of Turkey(Erciyes Univ Sch Medicine, 2021) Taylan, Gokay; Palabiyik, Orkide; Ozkalayci, Flora; Yilmaztepe, Mustafa Adem; Sivri, Nasir; Aksoy, YukselObjective: Although the risk factors for coronary artery disease (CAD) are well established, a significant gap still exists in understanding the pathology of atherosclerotic heart disease evolving without conventional risk factors. Therefore, genetic factors are considered to play a significant role in this setting. The present study aimed to assess the relationship between angiotensin 2 type 1 receptor (AT1R) A1166C gene polymorphism and CAD. Materials and Methods: Patients with documented CAD (n=121) were compared with controls with normal coronary arteries (n=121). CAD was diagnosed using a coronary angiography. The median age of participants was 59 +/- 12 years with an equal sex distribution. A comparison between the two groups with regard to the AT1R A1166C gene polymorphism was made through the amplification of DNA using polymerase chain reaction. Results: This study demonstrated that adenine-adenine and cytosine-cytosine (CC) genotypes were more frequent, yet adenine-cytosine genotype was less frequent among patients with CAD compared with controls [p=0.003), 95% confidence interval (CI)]. The AT1R A1166C gene polymorphism along with the CC genotype and C allele was found to be associated with CAD. Further, gender, hypertension, family history, age, and low levels of serum high-density lipoprotein also had a significant relationship with AT1R A1166C gene polymorphism. Conclusion: The present study suggested AT1R A1166C gene polymorphism, CC genotype, and C allele as potential risk factors for atherosclerotic CAD. Patients harboring these genetic variants should be under close supervision for the development of CAD.Öğe Atrial fibrillation in the setting of takotsubo cardiomyopathy: Just the tip of the iceberg?(Elsevier Ireland Ltd, 2018) Yalta, Kenan; Taylan, Gokay; Gurlertop, Yekta[Abstract Not Available]Öğe Atypical variants of takotsubo cardiomyopathy: mechanistic and clinical implications(Science Press, 2020) Yalta, Kenan; Yetkin, Ertan; Taylan, Gokay[Abstract Not Available]Öğe Baseline Characteristics of a Patient Cohort and Predictors of In-hospital MORtality in CORonary Care Units (MORCOR-TURK) Trial in Türkiye(Kare Publ, 2024) Yilmaz, Ahmet Seyda; Kahraman, Fatih; Ersoy, Ibrahim; Taylan, Gokay; Kaya, Emin Erdem; Aydin, Ertan; Karakayali, MuammerObjective: The MORtality in CORonary Care Units in T & uuml;rkiye (MORCOR-TURK) trial is a national registry evaluating predictors and rates of in -hospital mortality in coronary care unit (CCU) patients in T & uuml;rkiye. This report describes the baseline demographic characteristics of patients recruited for the MORCOR-TURK trial. Methods: The study is a multicenter, cross-sectional, prospective national registry that included 50 centers capable of 24 -hour CCU service, selected from all seven geographic regions of T & uuml;rkiye. All consecutive patients admitted to CCUs with cardiovascular emergencies between September 1-30, 2022, were prospectively enrolled. Baseline demographic characteristics, admission diagnoses, laboratory data, and cardiovascular risk factors were recorded. Results: A total of 3,157 patients with a mean age of 65 years (range: 56-73) and 2,087 (66.1%) males were included in the analysis. Patients with arterial hypertension [1,864 patients (59%)], diabetes mellitus (DM) [1,184 (37.5%)], hyperlipidemia [1,120 (35.5%)], and smoking [1,093 (34.6%)] were noted. Non -ST elevation myocardial infarction (NSTEMI) was the leading cause of admission [1,187 patients (37.6%)], followed by ST elevation myocardial infarction (STEMI) in 742 patients (23.5%). Other frequent diagnoses included decompensated heart failure (HF) [339 patients (10.7%)] and arrhythmia [272 patients (8.6%)], respectively. Atrial fibrillation (AF) was the most common pathological rhythm [442 patients (14%)], and chest pain was the most common primary complaint [2,173 patients (68.8%)]. Conclusion: The most common admission diagnosis was acute coronary syndrome (ACS), particularly NSTEMI. Hypertension and DM were found to be the two leading risk factors, and AF was the most commonly seen pathological rhythm in all hospitalized patients. These findings may be useful in understanding the characteristics of patients admitted to CCUs and thus in taking precautions to decrease CCU admissions.Öğe COVID-19 pandemic: a glimpse into newly diagnosed hypertensive patients(Lippincott Williams & Wilkins, 2021) Yetkin, Ertan; Taylan, Gokay; Yalta, Kenan[Abstract Not Available]Öğe Design and rationale for the ASSOS study: Appropriateness of aspirin use in medical outpatients a multicenter and observational study(Turkish Soc Cardiology, 2018) Celik, Oguzhan; Taylan, GokayObjective: The aim of this study was to describe the current status of aspirin use and the demographic characteristics of patients on aspirin for primary and secondary prevention of cardiovascular diseases. Methods: The Appropriateness of Aspirin Use in Medical Outpatients: A Multicenter, Observational Study (ASSOS) trial was a multicenter, cross-sectional, and observational study conducted in Turkey. The study was planned to include 5000 patients from 14 cities in Turkey. The data were collected at one visit, and the current clinical practice regarding aspirin use was evaluated (ClinicalTrials.gov number NCT03387384). Results: The study enrolled all consecutive patients who were admitted to the outpatient cardiology clinics from March 2018 until June 2018. Patients should be at least 18 years old, have signed written informed consent, and on aspirin (80-325 mg) therapy within the last 30 days. Cardiologists from the hospital participates in the study. Patients were divided into 2 categories according to presence or absence of atherosclerotic cardiovascular disease, namely secondary prevention group and primary prevention group, respectively. The appropriate use of aspirin in the primary and secondary prevention groups was assessed according to the European Society of Cardiology guidelines and US Preventive Services Task Force. The patients' gastrointestinal bleeding risk factors and colorectal cancer risk were evaluated. Conclusion: The ASSOS registry will be the most comprehensive and largest study in Turkey evaluating the appropriateness of aspirin use. The results of this study help understand the potential misuse of aspirin in a real-world setting.Öğe Evaluation of acute alterations in electrocardiographic parameters after cryoballoon ablation of atrial fibrillation and possible association with recurrence(Turkish Soc Cardiology, 2021) Uslu, Abdulkadir; Kup, Ayhan; Demir, Serdar; Gulsen, Kamil; Kanar, Batur Gonenc; Celik, Mehmet; Taylan, GokayObjective: This study aimed to evaluate the acute effect of cryoballoon ablation (CB-A) on electrocardiographic parameters that have been suggested to reflect heterogeneity in atrial conduction and ventricular repolarization. Methods: A total of 67 patients (52.6 +/- 13.2 years, 43 men) without any exclusion criteria who had undergone CB-A for atrial fibrillation (AF) between January 01, 2015, and December 31, 2018, constituted our study population. Electrographic recordings obtained before and after the ablation procedure on the same day were retrospectively evaluated for the P-wave dispersion, QTc dispersion, Tp-Te interval, and Tp-Te/QT ratio. The pre- and post-ablation values were tested for significant differences. The association of the possible CB-A-related changes in these parameters with AF recurrence during follow-up was evaluated. Results: P dispersion (30.1 +/- 6.8 vs. 35.9 +/- 9.4 ms, p<0.001), QT dispersion (20.7 +/- 7.5 vs. 24.0 +/- 8.8 ms, p<0.001), Tp-Te duration (on V5 83.6 +/- 8.1 vs. 110.2 +/- 9.5 ms, p<0.001), and Tp-Te/QT ratio (on V5 0.22 +/- 0.03 vs. 0.28 +/- 0.02, p<0.001) were observed to increase significantly after CB-A. There was no association between the magnitudes of change in any parameter and AF recurrence. Conclusion: CB-A had significant effects on electrocardiographic parameters related to atrial conduction and ventricular repolarization in the acute phase after CB-A. Further prospective studies are required to examine the time-related course of these alterations and their impact on clinical outcomes.Öğe Evaluation of Cardiac Autonomous Functions in Patients with Chronic Glomerulonephritis(Wiley, 2023) Cakir, Burcu; Taylan, Gokay[Abstract Not Available]Öğe Evaluation of Index of Cardioelectrophysiological Balance (iCEB) in Patients with Rheumatoid Arthritis(Aves, 2018) Ucar, Fatih Mehmet; Yilmaztepe, Mustafa Adem; Taylan, GokayObjective: Index of cardioelectrophysiological balance (iCEB), measured as QT interval divided by QRS duration, is defined recently as a new risk marker for arrhythmias. Increased or decreased iCEB is associated with malignant ventricular arrhythmias. We aimed to investigate the ventricular balance between the depolarization (changes in QRS duration) and depolarization (changes in the QT interval) of the cardiac action potential in rheumatoid arthritis (RA) patients by using iCEB. Materials and Methods: In total, 60 patients (mean age was 49.4 +/- 11.7 y and 61% of the patients were female) with RA and 60 control subjects (45.3 +/- 12.6 y and 60% of the patients were female) were enrolled. iCEB (QT/QRS) and iCEBc (heart rate-corrected QT (QTc)/QRS) rates were calculated from the 12-lead electrocardiogram. Results: iCEB and iCEBc were significantly higher in patients with RA than in control subjects (p<0.001 and p<0.001, respectively), and they were correlated with high-sensitivity C-reactive protein (hsCRP) levels (r=0.467, p<0.001 and r=0.479, p<0.001, respectively) Conclusions: Our results indicate that iCEB was increased in patients with RA. It is known that high iCEB is associated with torsade de Pointes (TdP) ventricular tachycardia. The increased frequency of ventricular arrhythmias in patients with RA may be TdP-related and can be clarified by the new index of balance between depolarization and repolarization (iCEB).Öğe Fever-induced type-1 Brugada pattern: A sign of revealed Brugada syndrome or just a Brugada phenocopy?(Polish Cardiac Soc-Polskie Towarzystwo Kardiologiczne, 2022) Yalta, Kenan; Taylan, Gokay; Ozturk, Cihan; Yalta, Tulin[Abstract Not Available]Öğe First Experience of Cardiac Device Implantation with Remote Cardiac Support System in Turkey(Galenos Publ House, 2022) Taylan, Gokay; Gok, Murat; Ozkan, Ugur; Altay, Servet; Yalta, Kenan[Abstract Not Available]Öğe Fluoroscopy time and scattered radiation during electrophysiology procedures: analysis of one-year data of a laboratory providing electrophysiology training(Taylor & Francis Ltd, 2021) Gulsen, Kamil; Akgun, Taylan; Kup, Ayhan; Uslu, Abdulkadir; Kanar, Batur Gonenc; Taylan, Gokay; Kayan, FethullahObjectives Patients and medical staff expose to significant radiation during electro-physiological (EP) procedures. There are few data regarding the leading factors of longer fluoroscopy time and higher scattered radiation in a laboratory giving EP training during those interventions. Material and methods The patients' recordings that underwent EP procedure in a single centre arrhythmia unit from February 2019 to January 2020 were examined. Prospectively collected data regarding procedure duration, fluoroscopy time and total air kerma, demographic characteristics of the patients, type of procedure, success of ablation and the use of electro anatomic mapping were retrospectively evaluated. Predictors of total air kerma were analysed with linear regression analysis. Results Study population consisted of 437 patients with a median age of 47 (39-56); 184 (42.1%) were male. Median fluoroscopy time was 768 (420-1320) seconds and median cumulative air kerma was 369 (191-750) mGy. Fluoroscopy time and cumulative air kerma were significantly lower in diagnostic EP studies compared to other procedures. There was no difference in terms of total air kerma between the procedures other than the diagnostic EP study. In multivariable linear regression analysis; body surface area, fluoroscopy time, not using the electro-anatomical mapping, unsuccessful ablation and atrial flutter ablation were predictors of total air kerma in EP studies performed by trainees. Conclusion Scattered radiation during EP procedures performed by in-training operators is related with some factors. Awareness about those may help to effort reducing the harmful effect of ionising radiation.Öğe Fontan Circulation Might be Associated with Peripartum Cardiomyopathy: A Review of Mechanistic and Clinical Aspects(Bentham Science Publ Ltd, 2021) Yalta, Kenan; Yetkin, Ertan; Taylan, GokayFontan operation has been defined as a palliative surgery connecting systemic venous return and pulmonary circulation in patients with certain forms of complex congenital heart disease (CHD). Fortunately, it has improved overall survival and chance of successful pregnancies among these patients. However, Fontan circulation (FC), as a potential trade-off, might be associated with specific late or post-gestational complications, including peripartum cardiomyopathy (PPCM) largely through its adverse effects on the placenta and inflammation-oxidation stress. Importantly, diagnosis of superimposed PPCM in women with FC might be a diagnostic challenge, requiring a high index of suspicion. Accordingly, the present paper aims to highlight the potential association of FC with PPCM evolution largely based on certain mechanistic and clinical perspectives.Öğe Fragmented QRS Pattern in Patients with COVID-19: Further Insights into Its Temporal and Mechanistic Features(Aves, 2022) Taylan, Gokay; Ozturk, Cihan; Yalta, Kenan[Abstract Not Available]
- «
- 1 (current)
- 2
- 3
- »
