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Öğe Cognitive evaluation with Montreal cognitive assessment (MOCA) test of patients with obstructive sleep apnea syndrome(Wiley-Blackwell, 2016) Gemici, Y. Inalkac; Celik, Y.; Sut, N.; Ozturk, L.[Abstract Not Available]Öğe GNB3 gene c.825C>T polymorphism and performance parameters in professional basketball players(Akademiai Kiado Zrt, 2014) Gulyasar, T.; Ozturk, L.; Sipahi, T.; Bayraktar, B.; Metin, G.; Yucesir, I.; Sut, N.This study has been conducted to determine whether mean values of peak oxygen consumption (VO2peak), anaerobic test parameters and knee isokinetic test measurements are different among guanine nucleotide-binding protein, beta-3 (GNB3) genotype groups in a group of basketball players. Methods: Seventy-two healthy male (mean age, 22.9 +/- 5.3 years) basketball players from the first division of national league participated. We studied GNB3 gene c. 825C>T (rs5443) polymorphism, then divided the subjects into three groups as CC (n = 21), CT (n = 35), and TT (n = 16). Mean VO2peak, Wingate anaerobic test results, and isokinetic knee muscle strength measurements were compared among the genotype groups. Results: Mean VO2peak (60.1 +/- 3.9; 56.7 +/- 3.6; and 57.8 +/- 3.3, respectively, p < 0.01), mean anaerobic minimum power (5.1 +/- 0.4; 5.3 +/- 0.5; and 4.4 +/- 0.5 W/kg, respectively, p < 0.001), mean anaerobic power drop (57.0 +/- 6.2; 54.2 +/- 6.9; and 62.9 +/- 5.3%, respectively, p < 0.001) were significantly different among the study groups, CC, CT, and TT. Individuals with TT genotype exerted lower performance in terms of isokinetic knee muscle strength. Conclusion: The presence of 825T-allele may impair athletic performance and may serve as a genetic marker of low capacity for athletic performance in male basketball players.Öğe Medial olivocochlear suppression in musicians versus non-musicians(Akademiai Kiado Zrt, 2019) Bulut, E.; Ozturk, G.; Tas, M.; Turkmen, M. T.; Gulmez, Z. D.; Ozturk, L.The medial olivocochlear efferent (MOCE) branch synapses with outer hair cells (OHCs), and the efferent pathway can be activated via a contralateral acoustic stimulus (CAS). The activation of MOCE can change OHC motile responses and convert signals that are capable of controlling the sensitivity of the peripheral hearing system in a frequency-specific manner. The aim of this study was to examine the MOCE system activity in professional musicians using transient evoked otoacoustic emission test and CAS. Musician group showed stronger suppression in all frequency bands in the presence of CAS.Öğe Spontaneous otoacoustic emission recordings during contralateral pure-tone activation of medial olivocochlear reflex(Akademiai Kiado Rt, 2017) Bulut, E.; Ozturk, L.We hypothesized that cochlear frequency discrimination occurs through medial olivocochlear efferent (MOCE)-induced alterations in outer hair cell (OHC) electromotility, which is independent from basilar membrane traveling waves. After obtaining informed consent, volunteers with normal hearing (n = 10; mean age: 20.6 +/- 1.2 years) and patients with unilateral deafness (n = 10; mean age: 30.2 +/- 17.9 years) or bilateral deafness (n = 8; mean age: 30.7 +/- 13.8 years) underwent a complete physical and audiological examination, and audiological tests including transient evoked otoacoustic emission and spontaneous otoacoustic emission (TEOAE and SOAE, respectively). SOAE recordings were performed during contralateral pure-tone stimuli at 1 and 3 kHz. SOAE recordings in the presence of contralateral pure-tone stimuli showed frequency-specific activation out of the initial frequency range of SOAE responses. Basilar membrane motion during pure-tone stimulation results from OHC activation by means of MOCE neurons rather than from a traveling wave. Eventually, frequency-specific responses obtained from SOAEs suggested that OHC electromotility may be responsible for frequency discrimination of the cochlea independently from basilar membrane motion.