Yazar "Ozkan, E." seçeneğine göre listele

Listeleniyor 1 - 3 / 3
  • Küçük Resim Yok
    Öğe
    Genetic characterization of indigenous anatolian water buffalo breed using microsatellite dna markers
    (Pagepress Publ, 2007) Soysal, M. I.; Ozkan, E.; Kok, S.; Occidente, M.; Tuna, Y. T.; Gurcan, E. K.; Matassino, D.
    One indigenous water buffalo population to Anatolia was characterised with 11 cattle autosomal microsatellite loci. A set of 4 cattle microsatellite loci was found to be polymorphic in the Anatolian buffalo genome. Genotyping of these polymorphic microsatellite loci revealed alleles ranging from 3 to 9. The observed heterozygosity ranged from 0.550 to 0.775 and the expected heterozygosity ranged from 0.494 to 0.815. The F(IS) value within each locus, changed from -0.101 to 0.205. Total F(IS) was 0.043 indicating that Anatolian water buffalo population samples seemed to be in Hardy- Weinberg expectation.
  • Küçük Resim Yok
    Öğe
    Involvement of spinal cannabinoid receptors in the antipruritic effects of WIN 55,212-2, a cannabinoid receptor agonist
    (Wiley, 2018) Bilir, K. A.; Anli, G.; Ozkan, E.; Gunduz, O.; Ulugol, A.
    Background. Cannabinoids have been used for their analgesic and euphoric effects for millennia, but recently the antipruritic effects of cannabis have been discovered. Considering the similarities between pain and itch sensations, we hypothesized that cannabinoid receptors may play a role in the antipruritic effects of cannabinoids. Aim. To analyse the role of the spinal cannabinoid receptors, CB1 and CB2, in the antipruritic effects of the cannabinoid agonist WIN 55,212-2. Methods. Male Balb/c mice weighing 20-30 g were used. Scratching behaviour in the mice was produced by injection of serotonin 5 g/50 L intradermally into the nape of the neck. Scratching of the site of injection by the hind paws was video-recorded for 30 min. After testing different doses of WIN 55,212-2 [1, 3 and 10 mg/kg intraperitoneally (IP)], the effects of the CB1 receptor antagonist, AM-251 [1 g/mouse administered intrathecally (IT)] and the CB2 receptor antagonist AM-630 (4 g/mouse IT) on the antipruritic effects of WIN 55,212-2 were studied using a rotarod apparatus. Results. WIN 55,212-2 (1, 3 or 10 mg/kg IP) dose-dependently decreased serotonin-induced scratches. The receptor antagonist CB1 partially reversed the effects of WIN 55,212-2 (P < 0.05); whereas CB2 had no statistically significant effect. WIN 55,212-2 impaired motor function only at the highest dose given (10 mg/kg, P < 0.05). Conclusions. Our findings support prior researches indicating that cannabinoids exert antipruritic effects. Moreover, our results show that the antipruritic effects of cannabinoids are partially mediated by spinal CB1 receptors.
  • Küçük Resim Yok
    Öğe
    IRRIGATION MANAGEMENT AND SOCIO-ECONOMIC IMPACTS OF WATER POLLUTION IN MEXICALI AND THRACE REGIONS
    (Scibulcom Ltd, 2006) Pombo, O. A.; Kubas, A.; Ozkan, E.; Yilmaz, F.
    The agricultural areas located at the Mexicali valley in Mexico are irrigated by the Colorado river across the 7 states of America. The water potential of the river basin is 2550 hm(3). In the Mexicali valley, 15 000 farms cultivate nearly 136 000 ha. Water management in the valley is implemented by 23 cooperatives which are named 'units' as well. Every unit has activities on two primary subjects. These are operation and protection units, i.e. operation unit is responsible for the distribution of the water to the producers and protection unit is involved for cleaning the irrigation ditches, their repairs and also maintenance for pumping units. The ownership of the water is related to farm ownership so that renting the farm means renting the water. Renting is very common and the farms are generally used for vegetable production. However, because of the water pollution, quality losses are observed for the agricultural products in the Mexicali valley. In the same manner, by the Meric river which comes from Bulgaria, various agricultural products are produced on the river basin. State Water Affairs, the General Directorate of Rural Services, cooperatives and unions and private irrigations are established for the irrigation of the region. The most important problem for irrigation in the region is water pollution. Every year in the summer, the decrease in the flow increases the pollution concentration of the water. Especially in paddy farming, quality and yield decreases are seen due to the pollution of the Meric river. The income and life quality of the farmers in the region are negatively affected by the pollution. In the last 50 years, environmental pollution became the most important issue that threatens the safety of the food. In the Mexicali and Thrace regions, for supplementing safe food, it must be taken into account that environmental pollution is a very important problem that concerns every country in the world and must be solved by international cooperation. In this study, irrigation management and socio-economic effects of water pollution will be analysed by comparing two regions having similar problems and solutions to problems will be developed.