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    Apical pouches with hypertrophic cardiomyopathy
    (Turkish Soc Cardiology, 2014) Ucar, Fatih Mehmet; Ozeke, Ozcan; Topaloglu, Serkan; Golbasi, Zehra
    [Abstract Not Available]
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    The Association between Platelet/Lymphocyte Ratio and Coronary Artery Disease Severity in Asymptomatic Low Ejection Fraction Patients
    (Korean Soc Cardiology, 2016) Ucar, Fatih Mehmet; Acar, Burak; Gul, Murat; Ozeke, Ozcan; Aydogdu, Sinan
    Background and Objectives: Coronary angiography (CAG) is generally needed in the setting of systolic heart failure (HF) with an unidentified etiology as a part of diagnostic strategy. On the other hand, the clinical value of this invasive strategy is largely unknown. Platelet-lymphocyte ratio (PLR) has recently emerged as a novel inflammatory index that may serve as an important predictor of inflammatory state and overall mortality. The present study aimed to search the predictive value of PLR in determining the extent of coronary atherosclerosis in asymptomatic low ejection fraction (EF) patients. Subjects and Methods: 156 asymptomatic heart failure (HF) subjects (without angina or HF symptoms, mean age: 58 years; to male: 71.2% were enrolled, and thereafter a CAG was performed. Gensini Score was used to determine the severity of coronary artery disease (CAD) on CAG. According to this scoring system, the overall study group was categorized into three distinct subgroups: control group with the score 0, mild atherosclerosis group with the score 0 to 20 and severe atherosclerosis group with the score of >20. Thereafter, a comparison was made among groups with regard to mean values of PLR. Results:The severe atherosclerosis group had a substantially higher level of mean PLR in comparison to other groups (p<0.001). Pre-CAG PLR levels as well as a variety of clinical variables including age, low density lipoprotein (LDL)-cholesterol demonstrated an independent correlation with Gensini score through a multivariate analysis. Conclusion: These findings suggest the potential association of high PLR levels with severe atherosclerosis in the setting of asymptomatic systolic HF. A simple measurement of PLR helps to identify the severity of coronary atherosclerosis prior to conducting coronary angiography.
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    Gamma-glutamyl transferase predicts recurrences of atrial fibrillation after catheter ablation
    (Taylor & Francis Ltd, 2016) Ucar, Fatih Mehmet; Ipek, Esra Gucuk; Acar, Burak; Gul, Murat; Tuncez, Abdullah; Ozeke, Ozcan; Geyik, Bilal
    Background Catheter ablation is a popular therapy of atrial fibrillation (AF). Gamma-glutamyl transferase (GGT) is known as a marker of oxidative stress. The objective of this study was to ascertain the relationship between levels of GGT and recurrence of AF after catheter ablation. Methods A total of 102 paroxysmal AF patients who underwent cryoballoon catheter ablation were enrolled. Serum samples were obtained to evaluate GGT levels before catheter ablation. Cox regression analysis was used to estimate the predictors of AF recurrence. Results Mean age of the cohort was 49.9 +/- 11.7 and 63% of the patients were male. After a mean follow-up of 20 months, 19 (23%) patients had AF recurrences. The baseline GGT levels were significantly higher in patients who had AF recurrence [27 U/L (17-36) vs 18 U/L (13-22), P=0.0021.The optimal cut-off value of GGT to predict AF recurrence was 23.5 U/L according to receiver operating characteristic curve analysis (area under the curve 0.72, P=0.002). In the multivariable Cox regression analysis, baseline GGT > 23.5 was the only independent predictor of AF recurrence (hazard ratio (HR) 4.47, 95% confidence interval [1.66-12.09], P=0.003). Conclusions Our results indicate that elevated GGT is associated with AF recurrence. A simple measurement of GGT may help us to identify high-risk patients undergoing catheter ablation for AF.
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    Single coronary artery with double coronary courses: Tips and tricks
    (Elsevier, 2019) Gul, Murat; Ozeke, Ozcan; Ozen, Anil; Ucar, Fatih Mehmet; Cay, Serkan; Aras, Dursun
    Congenital coronary artery anomalies are uncommon and the vast majority is diagnosed incidentally during coronary angiogram or necropsy. A single coronary artery is one of the most rarely seen coronary artery anomalies. Determination of its course (inter-arterial, intra-septal, pre-pulmonic or retro-aortic) is very important regarding its clinical significance. Avoiding the misdiagnosis of an unsuspected anomalous coronary artery is critical to the patient and it is always the angiographer's responsibility to accurately define the origin and course of the vessel. Cardiologists should be aware of simple clues in order to easily identify coronary anomalies.