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    Changes in antimicrobial resistance and outcomes of health care-associated infections
    (Springer, 2021) Aydin, Mehtap; Azak, Emel; Bilgin, Huseyin; Menekse, Sirin; Asan, Ali; Mert, Habibe Tulin Elmaslar; Yulugkural, Zerrin
    To describe the change in the epidemiology of health care-associated infections (HAI), resistance and predictors of fatality we conducted a nationwide study in 24 hospitals between 2015 and 2018. The 30-day fatality rate was 22% in 2015 and increased to 25% in 2018. In BSI, a significant increasing trend was observed for Candida and Enterococcus. The highest rate of 30-day fatality was detected among the patients with pneumonia (32%). In pneumonia, Pseudomonas infections increased in 2018. Colistin resistance increased and significantly associated with 30-day fatality in Pseudomonas infections. Among S. aureus methicillin, resistance increased from 31 to 41%.
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    The Effect of COVID-19 Rapid Antigen Testing in Education on Early Detection and Prevention of Epidemics: A Faculty Example from Trakya University
    (Bilimsel Tip Yayinevi, 2023) Davarci, Ismail; Eryildiz, Canan; Mert, Habibe Tulin Elmaslar; Davarci, Pinar Zehra; Hatipoglu, Osman Nuri; Kirilmaz, Eda; Ekuklu, Galip
    Introduction: To ensure the safe continuation of face-to-face education, there is ongoing discussion regarding the routine use of easily applicable tests. This study aimed to determine the effectiveness of the COVID-19 rapid antigen tests in the early diagnosis of COVID19 cases among university students studying face-to-face. Materials and Methods: Our study spanned a duration of eight weeks and included students from three different departments within a faculty. The first group of students underwent rapid antigen tests twice a week, with positive results confirmed by PCR testing. The second group was visited twice a week, and students displaying symptoms underwent both rapid antigen and PCR tests. The third group was monitored solely through the use of Hayat Eve Sigar (Life Fits Into Home) codes. To identify asymptomatic cases and students who did not report their symptoms in the second group, all volunteers on the final day of the study underwent screening using rapid antigen tests. The groups were compared based on the obtained results, and a questionnaire was administered to the students during each visit. This approach allowed for the investigation of factors associated with positive cases.Results: A total of 274 students participated in our study, with 114 (41.6%) in the first group, 96 (35.0%) in the second group, and 64 (23.4%) in the third group. The rate of detecting the cases in the first group was significantly higher than in the second and third Conclusion: The obtained findings indicate that COVID-19 rapid antigen tests, as mentioned, can serve as a screening tool for the early detection of cases and prevention of further spread among students during face-to-face education. These results align with the criteria established by international organizations and epidemiological standards. By screening all participating students, the potential for bias is minimized, enabling the identification of asymptomatic individuals who may unknowingly transmit the virus.
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    Mucormycosis in a Patient with Uncontrolled Diabetes Mellitus
    (Galenos Yayincilik, 2022) Inal, Mehmet Turan; Memis, Dilek; Hanci, Pervin; Gunbay, Gokhan; Keles, Samet; Mert, Habibe Tulin Elmaslar; Garip, Ruveyde
    Mucormycosis; is a rapidly progressive fungal infection due to filamentous fungi of the mucoraceae family. In this case report, we aimed to present the diagnosis and treatment modalities of a patient who developed rhinoorbital mucormycosis. A 54-year-old patient with a history of hypertension applied to the emergency department with a complaint of wound in the mouth that started four days ago. In the examinations performed here, the patient was diagnosed with diabetic ketoacidosis. In the examination of the patient, it was found that there was a necrotic wound on the left hard palate, a necrotic wound extending from the left inferior turbinate to the nasopharynx, and hyphae in the nasal passage. The patient underwent an aggressive debridement operation on the third day, due to the growth in the fungal culture. In the following clinical examination of the patient, ketone in the urine became negative, and his acidosis status improved. On the same day, the patient was treated with a positive coronavirus disease-2019 (COVID-19) polymerase chain reaction. After 15 days of treatment, the patient died due to COVID-19 pneumonia. Mucormycosis should be doubtful in patients presenting with uncontrolled diabetes mellitus and severe sinoorbital infection. All physicians following diabetic ketoacidosis should be vigilant against this rapidly progressing disease with high mortality.