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    Are breast milk adipokines affected by maternal dietary factors?
    (Walter de Gruyter Gmbh, 2018) Kocaadam, Betul; Koksal, Eda; Turkyilmaz, Canan
    Background: Maternal diet and gestational age of infant may affect the composition of breast milk. The aim of this study was to evaluate the relationship between breast milk adiponectin and leptin levels of mothers delivering preterm and term infants and maternal diet. Methods: Sixty-five mothers (31 preterm, 34 term) were included in the study. General information about parents and infants and food consumption of mothers were determined through a questionnaire. Milk samples were taken from mothers during the period between the 15th and 30th day after birth (mature milk). For the evaluation of maternal diet, the nutrient adequacy ratio (NAR) and mean adequacy ratio (MAR) were used. Results: According to MAR, 71.0% of preterm mothers' and 79.4% of term mothers' dietary adequacy was categorized as "good", and none of the mothers fell into the "insufficient" category (p > 0.05). The median (interquartile range [IQR]) level of adipokines was found to be higher in preterm than in term mothers (24.6 [14.3] ng/mL; 22.9 [9.7] ng/mL for adiponectin and 2.0 [2.5] ng/mL; 0.0 [2.3] ng/mL for leptin, respectively) (p > 0.05). A negative correlation was found between the leptin level and intake of unsaturated fatty acids, protein NAR and meat, poultry and fish consumption in preterm mothers (p < 0.05). A positive correlation was found between leptin concentration and MAR, protein, calcium, potassium NAR and consumption of dairy products in term mothers (p < 0.05). In the regression model, gestational age and MAR are important predictors of leptin. Conclusions: These results show that maternal diet is related to the leptin content in breast milk.
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    Association between adherence to the Mediterranean diet with anthropometric measurements and nutritional status in adolescents
    (Aran Ediciones, S L, 2023) Kocaadam-Bozkurt, Betul; Ermumcu, Merve Seyda Karacil; Govez, Nazlican Erdogan; Bozkurt, Osman; Akpinar, Serife; Celik, Ozge Mengi; Koksal, Eda
    Background: adolescence is a critical period for developing healthy eating habits. It is crucial to evaluate and encourage adherence to the Mediterranean diet, a sustainable and healthy diet model in this age group.Objective: this study aimed to evaluate the relationship between adherence to the Mediterranean diet and anthropometric measurements and nutritional status in Turkish adolescents.Material and methods: the demographic characteristics, health information, nutritional habits, physical activity status, and 24-hour dietary recall of the adolescents were obtained with a questionnaire. Adherence to Mediterranean diet was evaluated with the Mediterranean-Style Dietary Pattern Score (MSDPS).Results: a total of 1,137 adolescents (mean age 14.0 & PLUSMN; 1.37 years) were included; 30.2 % of the boys and 39.5 % of the girls were overweight/ obese. The median (interquartile range) value of the MSDPS was 10.7 (7.7), and this value was 11.0 (7.6) for the boys and 10.6 (7.4) for the girls (p > 0.05). The levels of protein, fiber, vitamin A, vitamin C, folate, vitamin B12, iron, magnesium, zinc, and potassium intake increased with adherence to Mediterranean diet (p < 0.001). Age, parental education level, body mass index (BMI), waist circumference, and skipping meals affected MSDPS.Conclusion: adolescents' adherence to the Mediterranean diet was low and correlated with some anthropometric measures. Increasing adherence to the Mediterranean diet may contribute to preventing obesity and adequate and balanced nutrition in adolescents.
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    Association between ecological footprint awareness and health literacy in adults: a population-based study from Turkey
    (Taylor & Francis Ltd, 2024) Celik, Ozge Mengi; Koksal, Eda; Akpinar, Serife; Kocaadam-Bozkurt, Betul; Govez, Nazlican Erdogan; Daziroglu, Merve Esra Citar; Ermumcu, Merve Seyda Karacil
    This study aimed to determine the relationship between health literacy and ecological footprint which is an indicator of sustainability and environmental impact and to examine the factors that may affect them. It was found that 20.3% of individuals have inadequate, 43.7% problematic, 26.1% sufficient and 10.0% excellent health literacy levels. There were differences in age, education level and BMI classification according to Ecological Footprint Awareness Scale score quartiles and health literacy levels (p < 0.05). It was determined that age and Turkey Health Literacy Scale score had effect on ecological footprint awareness. Individuals with a high level of health literacy have a high awareness of their ecological footprint. The increase in people's health literacy levels and ecological footprint awareness with age can be interpreted as the increase in people's education and knowledge levels and their awareness levels against the protection of nature and the environment.
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    Brucella Septic Arthritis and Abscess in Hand Joint
    (Aves, 2020) Alkan-Ceviker, Sevil; Gunal, Ozgur; Elmaslar-Mert, Habibe Tulin; Koksal, Eda
    Brucellosis can affect all kinds of organs and can cause a wide range of clinical findings. The incidence of osteoarticular involvement in brucellosis has been reported to vary between 10-85% in various regions of the world. The most affected joints are knee, hip and ankle, respectively. However, it can affect all joints. Antibodies do not occur in 1-5% of cases with brucellosis and this is called seronegative brucellosis. It should be kept in mind that culture helps in definitive diagnosis for seronegative cases. In this case report, we aimed to emphasize that brucellosis should be considered in the differential diagnosis of peripheral arthritis, especially in older patients with risk factors in endemic areas even if serological tests were negative, and culture is essential to confirm the diagnosis.
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    Do the adiponectin and leptin levels in preterm and term breast milk samples relate to infants' short-term growth?
    (Cambridge Univ Press, 2019) Kocaadam, Betul; Koksal, Eda; Ozcan, Kudret Ebru; Turkyilmaz, Canan
    Adiponectin and leptin are involved in appetite control and body weight regulation. We aimed to evaluate the relationship between breast milk adipokine levels and short-term growth of preterm and term infants. Thirty-one preterm (median=35.3 weeks) and 34 term (median=38.7 weeks) infants were enrolled. Enzyme-linked immunosorbent assay was used to detect adipokines in mature milk. Infant growth was followed during the first 3 months. Although weight gain in the first month was insufficient, positive linear growth was observed in the following months for preterm infants, while term infants had positive steady linear growth. The median level of adipokines was found to be higher in preterm infants (P>0.05). Adiponectin showed significant negative correlations with some anthropometric measurements of term infants. However, in preterm infants, adiponectin was negatively correlated with length increment and positively correlated with body mass index (BMI) increment in the second-third month. In addition, leptin was negatively associated with the head circumference at birth in preterm infants and the triceps skinfold thickness increment in the first-second month term infants (P<0.05). In linear regression models, while gestational age, adiponectin and leptin were not related, maternal age and pre-pregnancy BMI had effects on body weight increment in 0-1 months (P<0.05). In conclusion, adiponectin may affect short-term growth, while leptin has no important effect. It would be beneficial to carry out longitudinal studies to evaluate the effects of these adipokines on the growth of infants.
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    Effects of Diurnal Ramadan Intermittent Fasting on Cardiometabolic Risk Factors and Sleep Quality in Healthy Turkish Adults
    (Taylor & Francis Inc, 2022) Celik, Ozge Mengi; Kocak, Tevfik; Koksal, Eda
    This study aimed to evaluate the effect of diurnal Ramadan fasting on cardiometabolic risk factors (blood glucose, lipid profile, inflammatory cytokines) and sleep quality in healthy Turkish adults. This prospective observational study was conducted with a total of 32 individuals (12 males, 20 females) who were aged between 19-32 years and fasted for 25 or more continuous days in Ankara, Turkey between 1 Ramadan 1442 and 30 Ramadan 1442. Individuals applied fasting for 16 hours in the spring season. Blood samples were taken after at least 8 hours of fasting, anthropometric measurements were taken and sleep quality was assessed using The Pittsburgh Sleep Quality Index (PSQI) at the beginning and the end of Ramadan. There was a significant decrease in body mass index (BMI), C-reactive protein (CRP), and tumor necrosis factor-alpha (TNF-alpha) levels during Ramadan fasting (p < .005). There were no changes in lipid profiles and sleep quality. There was a significant increase in fasting blood glucose levels (p < .05); however, this change is within normal limits. There was also a significant relationship between BMI and CRP, IL-6, and TNF-alpha levels (p < .05). The diurnal Ramadan fasting did not affect lipid profiles and sleep quality in healthy Turkish subjects. However, decreased BMI and inflammatory cytokine levels were observed at the end of Ramadan fasting. More studies are needed to clarify the role of Ramadan fasting in healthy populations.