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Öğe Balloon Shaft Fracture: A Nightmare Scenario in the Setting of Percutaneous Coronary Intervention(H M P Communications, 2023) Akkus, Omer Ferudun; Gok, Murat; Karahan, Furkan; Canbaz, Suat; Yalta, Kenan[Abstract Not Available]Öğe First Experience of Cardiac Device Implantation with Remote Cardiac Support System in Turkey(Galenos Publ House, 2022) Taylan, Gokay; Gok, Murat; Ozkan, Ugur; Altay, Servet; Yalta, Kenan[Abstract Not Available]Öğe The first septal perforating artery in the setting of percutaneous coronary interventions: More than just a side branch(Polish Cardiac Soc, 2024) Yalta, Kenan; Gok, Murat; Gurdogan, Muhammet[Abstract Not Available]Öğe How to Manage Implantable Cardiac Defibrillator Protection in an Implantable Cardiac Defibrilla tor-Dependent Patient Undergoing Palliative Radiotherapy?(Kare Publ, 2023) Ozturk, Cihan; Yilmaz, Efe; Taylan, Gokay; Gok, Murat; Yalta, Kenan[Abstract Not Available]Öğe Impact of chronic total occlusion in a non-infarct-related coronary artery on contrast-associated nephropathy in acute ST-elevation myocardial infarction(Taylor & Francis Ltd, 2023) Gok, Murat; Kurtul, Alparslan; Taylan, Gokay; Ozturk, Cihan; Cakir, Burcu; Yilmaz, Efe; Altay, ServetObjectives Co-existing chronic total occlusion (CTO) in a non-infarct-related artery (IRA) might serve as an important trigger of adverse outcomes in ST-segment elevation myocardial infarction (STEMI). Therefore, we planned to analyse the potential impact of non-IRA CTO on the evolution of contrast-associated nephropathy (CAN) in STEMI patients managed with primary percutaneous coronary intervention (P-PCI). Methods A total of 537 subjects with STEMI undergoing P-PCI during the first 12 h after the onset of their symptoms were enrolled in this retrospective study. The subjects were categorised based on the angiographic presence of non-IRA CTO. Moreover, the subjects were also divided into 2 groups based on their CAN status following P-PCI (CAN (+) and CAN (-)). Results Co-existing non-IRA CTO was demonstrated in 86 subjects (16%). During the hospitalisation period, we identified 81 (15.1%) subjects with CAN. Subjects with non-IRA CTO had a significantly higher incidence of CAN compared with those without (56 [12.4%] vs 25 [29.1%], respectively, p < 0.001). In a logistic regression analysis, an existing non-IRA CTO (odds ratio: 2.840, 95%CI: 1.451-5.558, p = 0.002), as well as age, haemoglobin, diabetes mellitus, creatinine, and white blood cell count, were independent of predictors of CAN. Conclusion In STEMI patients managed with P-PCI, a co-existing non-IRA CTO had an independent association with the evolution of CAN.Öğe Integrating the Left Atrium Diameter to Improve the Predictive Ability of the Age, Creatinine, and Ejection Fraction Score for Atrial Fibrillation Recurrence After Cryoballoon Ablation(Kare Publ, 2023) Taylan, Gokay; Gok, Murat; Kurtul, Alparslan; Uslu, Abdulkadir; Kup, Ayhan; Demir, Serdar; Gulsen, KamilBackground: Several clinical trials have assessed predictors for atrial fibrillation recur rence following cryoballoon catheter ablation. With these predictors, a practical and new scoring system can be developed to evaluate atrial fibrillation recurrence. The present study aimed to analyze the predictive value of the age, creatinine, and ejection fraction -left atrium score for potential recurrence of atrial fibrillation following cryoballoon cath- eter ablation in patients with symptomatic paroxysmal or persistent atrial fibrillation. Methods: We retrospectively analyzed records of patients undergoing cryoballoon cath- eter ablation. atrial fibrillation recurrence was defined as an emerging atrial fibrillation episode around 12-month follow-up (with the exclusion of a 3-month blanking period). Univariate and multivariate analyses were performed to assess predictors of atrial fibrilation recurrence. In addition, receiver operating characteristic analysis was harnessed to evaluate the performance of the age, creatinine, and ejection fraction, left atrium score in determining the risk of atrial fibrillation recurrence. Results: The study population comprised 106 subjects (age 52 +/- 13 years, 63.2% women) with paroxysmal (84.9%, n = 90) or persistent (15.1%, n = 16) atrial fibrillation. age, cre- atinine, and ejection fraction, left atrium score was significantly higher in subjects with atrial fibrillation recurrence in comparison to those with the maintenance of sinus rhythm. However, on multivariate logistic regression analysis, only the age, creatinine, and ejection fraction, left atrium score (OR = 12.93, 95% CI: 2.22-75.21, P = .004) served as an independent predictor of atrial fibrillation recurrence following cryoballoon catheter ablation. Conclusion: Age, creatinine, and ejection fraction, left atrium score had an independent association with the risk of atrial fibrillation recurrence in subjects with atrial fibrillation undergoing cryoballoon catheter ablation. Therefore, this score might potentially serve as a useful tool for risk stratification of patients with atrial fibrillation.Öğe Low sCD163/TWEAK Ratio at First Day After Acute Myocardial Infarction Associated with Adverse Cardiac Remodeling in Non-Elderly Patients(Russian Heart Failure Soc, 2022) Altintas, Mehmet Sait; Eyerci, Nilnur; Karayigit, Orhan; Demirtas, Bekir; Gok, Murat; Kiziltunc, EmrullahAim In this study, we aimed to investigate the role of sCD163 /tumor necrosis factor-like weak apoptosisinducing (TWEAK) ratio in cardiac remodeling in non-elderly patients diagnosed with first acute myocardial infarction (MI). Material and Methods Forty-four patients (age ranges: 40-64 years) diagnosed with first-time acute ST-elevation MI in the emergency department were evaluated with cardiac magnetic resonance (CMR) imaging. Adverse remodeling (AR) was defined the increases of left ventricular end-diastolic volume by =12 % by CMR at 6-month post-MI TWEAK and sCD163 were measured at the first day (baseline), 2 weeks and 6 weeks post-MI. Results The average age of patients included in the study was 53.6 +/- 5.1 years. AR was detected in 18 patients at the 6 months post-MI. At the first day post-MI, median sCD163 concentration (116 069 vs 86 394 pg/ mL, p=0.040) and median TWEAK concentration (759.4 vs 220.1 pg /mL, p<0.001) were higher in AR group compared to group without AR (the non-AR group), median sCD163 /TWEAK ratio (101.4 vs. 406.8; p<0.001) was lower. At the first day post-MI, concentrations of TWEAK and sCD163 showed a positive correlation in AR group and group without AR s. At 2 weeks post-MI, positive correlation continued in the non-AR group, but no significant correlation was found in the AR group. At the first day post-MI, sCD163/TWEAK ratio was higher diagnostic performance compared to TWEAK and sCD163. Conclusion In the early phase post-MI, the relationship between sCD163 - TWEAK may have an important role in AR pathogenesis. A lower sCD163 /TWEAK ratio on the first day after MI was associated with an increase in left ventricular end-diastolic volume after 6 months of follow-up.Öğe Management of Coronary Ostial Stenosis with Drug Coated Balloons: Technical and Clinical Aspects(Aves, 2022) Yalta, Kenan; Taylan, Gokay; Gok, Murat; Yalta, Tulin[Abstract Not Available]Öğe Preinterventional pan-immune-inflammation value as a tool to predict postcontrast acute kidney injury among acute coronary syndrome patients implanted drug-eluting stents: a retrospective observational study(Taylor & Francis Ltd, 2024) Kurtul, Alparslan; Gok, MuratWe evaluated the value of pan-immune-inflammation value (PIV) in predicting the risk for postcontrast acute kidney injury (PCAKI), an important complication following percutaneous coronary intervention (PCI) in acute coronary syndrome (ACS) patients. Medical records of 839 ACS patients underwent PCI between June 2019 and December 2022 were retrospectively analyzed. Patients were divided into two groups: PCAKI (-) and PCAKI (+). PCAKI was defined as a >= 0.5 mg/dL and/or a >= 25% increase in serum creatinine within 72 h after PCI. The PIV was computed as [neutrophils x platelets x monocytes]divided by lymphocytes. The mean age was 60.7 +/- 12.9 years. PCAKI was detected in 105 (12.51%) patients. PIV was higher in the PCAKI (+) group compared to PCAKI (-) group (median 1150, interquartile range [IQR] 663-2021 vs median 366, IQR 238-527, p < 0.001). Receiver operating characteristic curve analysis showed that the best cutoff of PIV for predicting PCAKI was 576 with 81% sensitivity and 80% specificity. PIV was superior to neutrophil-lymphocyte ratio and platelet-lymphocyte ratio for the prediction of PCAKI (area under curve:0.894, 0.849 and 0.817, respectively, p < 0.001 for all). A high PIV was independently correlated with PCAKI (<= 576 vs. >576, odds ratio [OR] 12.484, 95%confidence interval [CI] 4.853-32.118, p < 0.001) together with older age (OR 1.058, p = 0.009), female gender (OR 4.374, p = 0.005), active smoking (OR 0.193, p = 0.012), left ventricular ejection fraction (OR 0.954, p = 0.021), creatinine (OR 10.120, p < 0.001), hemoglobin (OR 0.759, p = 0.019) and c-reactive protein (OR 1.121, p = 0.002). In conclusion, a high PIV seems to be an easily assessable tool that can be used in clinical practice for predicting the risk of PCAKI in ACS patients implanted drug-eluting stents.Öğe The Role of Interferons in Cardiac Remodeling after Acute Myocardial Infarction(Coll Physicians & Surgeons Pakistan, 2022) Eyyupkoca, Ferhat; Eyerci, Nilnur; Ozkan, Can; Kocak, Ajar; Gok, Murat; Ercan, KarabekirObjective: To determine the relationship of serial interferon (IFN) measurements and adverse cardiac remodeling (AR) after myocardial infarction (MI). Study Design: Observational multi-centre study. Place and Duration of Study: Departments of Cardiology of Diskapi Yildirim Beyazit Training and Research Hospital, Ataturk Training and Research Hospital, Numune Training and Research Hospital, and Dr. Nafiz Sincan Korez State Hospital, Turkey, from June 2015 to June 2020. Methodology: Forty-seven patients with acute MI were included. IFN levels were measured on the first day and at 14 days and 45 days post-MI. Reverse cardiac remodeling (RR) and AR were defined as the reduction of left ventricular end-diastolic volume by-12% and increases of-12% by cardiac magnetic resonance imaging at the 6-month follow-up. Statistical significance was accepted as p<0.05. Results: Median IFN-alpha (50.1 vs. 34.8 pg/mL, p=0.035), IFN-beta (39.1 vs. 23.0 pg/mL, p=0.013), and IFN-gamma (26.7 vs. 18.5 pg/mL, p=0.023) levels on the first day post-MI were higher in the AR group compared to the RR group. At 14 days post-MI, IFN levels had decreased in the AR group, while they had not changed in the RR group. At 45 days post-MI, IFN levels were similar between the AR and RR groups. High IFN-alpha level on the first-day post-MI was an independent predictor of AR (OR: 1.23, 95% CI: 1.06-1.43, p=0.008). Conclusion: High IFN levels in the acute phase post-MI are associated with AR. Among IFNs, IFN-alpha is an important predictor of AR. Stable IFN levels appear to be associated with cardiac healing.Öğe Sacubitril-valsartan: Hope or hype in the battle against cardiotoxicity due to cancer treatment?(Polish Cardiac Soc-Polskie Towarzystwo Kardiologiczne, 2022) Yalta, Kenan; Gok, Murat; Ozturk, Cihan; Yalta, Tulin[Abstract Not Available]Öğe Serum Prealbumin: a potential predictor of Right Ventricular Dysfunction in patients receiving programmed hemodialysis(Assoc Medica Brasileira, 2022) Gok, Murat; Kurtul, Alparslan; Taylan, Gokay; Sayilar, Emel Isiktas; Yalta, KenanOBJECTIVE: Prealbumin has been a reliable marker to predict protein energy malnutrition and hypercatabolic state. In this analysis, we particularly aimed to investigate the potential association between serum prealbumin levels and right ventricular dysfunction in patients receiving programmed hemodialysis. METHODS: A total of 57 subjects were included in the analysis. The subjects were then categorized into two groups: right ventricular dysfunction (n=18) and non-right ventricular dysfunction (n=39) groups. In all patients, detailed transthoracic echocardiography (following hemodialysis) were performed along with the evaluation of complete blood count, routine biochemistry parameters, and, in particular, serum prealbumin levels. RESULTS: Mortality rate at 3 years was found to be significantly higher in the right ventricular dysfunction group (p=0.042). Serum prealbumin levels were also significantly lower in the right ventricular dysfunction group compared with the non-right ventricular dysfunction group (23.83??8.50 mg/dL versus 31.38??6.81 mg/dL, p=0.001). In the receiver operating characteristics curve analysis, a prealbumin cutoff value of <28.5 mg/dL was found to predict right ventricular dysfunction, with a sensitivity of 67% and a specificity of 62% (area under the curve: 0.744). In the correlation analysis, a moderate yet significant positive correlation was demonstrated between serum prealbumin and tricuspid annular plane systolic excursion (r=0.365, p=0.005). CONCLUSION: This study suggests that low serum prealbumin might serve as a potential predictor of right ventricular dysfunction (and its clinical consequences) in patients receiving programmed hemodialysis.Öğe Takotsubo syndrome during breastfeeding: Further insights into prolactin and its implications(Elsevier Espana Slu, 2023) Yalta, Kenan; Ozturk, Cihan; Gok, Murat; Yalta, Tulin[Abstract Not Available]
