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    Clinical comparison of the ocular blood flow tonograph and the Goldmann applanation tonometer
    (Wichtig Editore, 1998) Esgin, H; Alimgil, ML; Erda, S
    Purpose. To compare the IOP readings of an ocular blood flow (OBF) tonograph (OBF Labs UK Ltd) with Goldmann applanation tonometry. Methods. 194 patients were studied. In group 1, the software version 8.2 of the OBF tonograph was used in 214 eyes of 107 patients and in group 2, the 11.2 version of the tonograph was used in 174 eyes of 87 patients. Results. We found 63% of the OBF tonograph readings to be within +/-2 mm Hg of the Goldmann applanation tonometry readings in group 1 and 60% in group 2. In group I the correlation coefficient between the readings of the two instruments was 0.71 and 0.82 in group 2. The mean value for the paired differences in group 1 was -1.34+/-2.75 mm Hg overall and -1.04+/-2.91 mm Hg overall in group 2. There was a significant difference between the Goldmann applanation tonometer and OBF tonograph readings in the 8-10 mm Hg interval (p<0.001) in group I, but not in group 2 (p>0.1). Conclusions. The 11.2 version of the OBF tonograph is more accurate than the 8.2 version and measures IOP in a manner that corresponds well to the Goldmann applanation tonometer in the 8-10 mm Hg and 21-29 mm Hg intervals. It corresponds fairly well in the 11-20 mm Hg interval.
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    The effect of systemic hypertension on pulsatile ocular blood flow in diabetic patients
    (Wiley, 2001) Esgin, H; Alimgil, ML; Erda, S
    Purpose: To determine the haemodynamics of the ciliary choroidal system in diabetics with or without systemic hypertension, Methods: 90 eyes of 45 diabetic patients were included into the study. Patients were divided into two groups based on the presence of systemic hypertension, The pulsatile component of the total ocular blood flow in diabetics with or without hypertension was analyzed using ocular blood flow tonograph (OBF Labs, UK), The control group was comprised of 40 age-matched eyes of 20 volunteers with no ocular or systemic disease. Results were compared with the control group. Results: Pulse amplitude (PA), pulse volume (PV) and pulsatile ocular blood flow (POBP) were significantly lower (p<0.05) in diabetics without systemic hypertension than the controls. In diabetics with hypertension, although the systolic and diastolic blood pressures were significantly higher than the control group, there was not any statistically significant difference (p>0.05) between PA, PV and POBF results, Conclusion: POBP was found to be lower in diabetics without hypertension compared to the controls. Such a presence of systemic hypertension may increase the choroidal blood flow in diabetics.
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    Ocular pulse amplitude in patients with Graves' disease
    (Scriptor Publisher, 1999) Alimgil, ML; Benian, Ö; Esgin, H; Erda, S
    Purpose: The purpose of this study was to evaluate the ocular pulse amplitude changes in patients with Graves' disease. Methods: The pulse amplitudes of 31 patients with Graves' disease were measured with the OBF-Tonograph (OBF Labs UK). Ail patients were in the euthyroid phase of the disease. 17 patients (Group I) had no ocular involvement or only mild lid retraction. 14 patients (Group II) had either proptosis and/or extraocular muscle involvement. Only the worst involved eye of each patient was included into the study. Results: There was no statistically significant difference between the two groups among the parameters which might influence the pulse amplitude measurement. The pulse amplitude was statistically significantly lower in Group II than in Group I(2.34+/-0.79 and 3.22+/-0.94 mmHg respectively p<0.013). Conclusion: Pulse amplitude measurements may be an important discrimination and classification parameter for patients with ophthalmic Graves' disease.