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Öğe 18F-FDG PET-CT features of primary primitive neuroectodermal tumor of the chest wall(Turkish Soc Radiology, 2009) Demir, Mustafa Kemal; Kosar, Filiz; Sanli, Yasemin; Esmaeilzadeh, Safa; Urer, Halide NurA case of primary primitive neuroectodermal tumor (PNET) of the chest wall in an adolescent is presented with imaging findings including 18F-fluorodeoxyglucose (18F-FDG) positron-emission computed tomography (PET-CT). To date, radiological description of the PNET of the chest wall has mainly been carried out by radiographic analysis, computed tomography (CT), and magnetic resonance imaging (MRI). We demonstrated that 18F-FDG PET-CT visualizes the active focus of glucose metabolism of PNET of the chest wall and is effective for the preoperative evaluation of patients with this tumor.Öğe Can MR imaging be used to reliably differentiate proliferative myositis from myositis ossificans? Response(Radiological Soc North America, 2008) Demir, Mustafa Kemal[Abstract Not Available]Öğe Case 142: Susac Syndrome(Radiological Soc North America, 2009) Demir, Mustafa Kemal[Abstract Not Available]Öğe Congenital upper thoracic spondyloptosis with multiple other associated anomalies(Wiley-Blackwell Publishing, Inc, 2009) Alicioglu, Banu; Demir, Mustafa Kemal; Durmus, Yavuz[Abstract Not Available]Öğe CT-angiographic demonstration of hepatic collateral pathways due to superior vena cava obstruction in Behcet disease(Turkish Soc Radiology, 2010) Temizoz, Osman; Genchellac, Hakan; Yekeler, Ensar; Demir, Mustafa Kemal; Unlu, Ercument; Ozdemir, HuseyinBehcet disease (BD) is a chronic multisystemic inflammatory disorder, mainly characterized by recurrent oral and genital ulcers, skin lesions, and uveitis. Large vein thrombosis in BD is unusual; when present, it is most frequently seen in the inferior or superior vena cava (SVC). The authors describe an unusual hepatic pseudolesion caused by abnormal focal enhancement through collateral pathways to the liver in two BD patients with SVC occlusion on three-dimensional multi-detector computed tomography, using volume rendering and maximum intensity projection techniques. BD should be suspected in patients presenting a focal increased hepatic enhancement area with collaterals caused by occlusion of the SVC without evidence of a hypercoagulable state or malignant mediastinal or thoracic venous inlet obstruction.Öğe Dermatofibroma mimicking malignancy on integrated F-18 fluorodeoxyglucose PET-CT(Turkish Soc Radiology, 2009) Demir, Mustafa Kemal; Ozdemir, Huseyin; Genchallac, Hakan; Altaner, Semsi; Kartal, OezcanA 31-year-old female with a history of ovarian cancer underwent an F-18 fluorodeoxyglucose (FDG) positron emission tomography-computed tomography (PET-CT) scan. The PET-CT demonstrated focal nodular uptake in the subcutaneous tissue of the back adjacent to the paraspinal muscles. Color Doppler ultrasonography examination demonstrated a vascular solid mass. The patient underwent biopsy followed by excision. The pathologic diagnosis was dermatofibroma. Although benign, dermatofibromas can have intense FDG uptake.Öğe Detection and quantification of the parenchymal abnormalities in emphysema using pulmo-CT(Pergamon-Elsevier Science Ltd, 2007) Temizoz, Osman; Etlik, Omer; Sakarya, Mehmet Emin; Uzun, Kursat; Arslan, Halil; Harman, Mustafa; Demir, Mustafa KemalWe aimed to determine the degree and extent of parenchymal abnormalities on pulmo-CT in patients with emphysema. The study group consisted of 29 patients (18 male, I I female; mean age 57.9. L 13). The diagnosis was based on clinical symptoms, pulmonary function tests (PFT) values, and chest CT findings. All of the patients CT scans were obtained during suspended deep inspiration from the apices to the costophrenic angles. The mean lung attenuation (MLD) and parenchymal abnormalities related to emphysema were quantitatively calculated with tables, histograms and graphics at the whole lung. The lung density measurements revealed a mean density of -898.48 +/- 51.37 HU in patients with emphysema and -825.1 +/- 25.5 HU in control group. In addition, mean percentage of subthreshold attenuation values was found as 12.03 +/- 15.75 and 1.07 +/- 0.83 in patients with emphysema and control group, respectively. Compared with control group, the patients with emphysema had a significantly lower inspiratory MLD (p < 0.05). Additionally, statistically significant correlations were seen between the MLD and percentage of subthreshold values (r = 0.44, p < 0.05). In contrast, there was poor correlation between PFT measurements and the subthreshold values. In conclusion, pulmo-CT is a quick, simple method for quantitative confirmation of the presence of parenchymal abnormalities of lung as mosaic attenuation and should be used in combination with other radiological methods and PFT as it gives additional information to routine examinations in patients with emphysema. (c) 2007 Elsevier Ltd. All rights reserved.Öğe Diagnosis please comment(Radiological Soc North America, 2007) Demir, Mustafa Kemal[Abstract Not Available]Öğe Differential diagnosis of spinal epidural meningioma and hemangioma at MR imaging(Radiological Soc North America, 2007) Demir, Mustafa Kemal; Ozdemir, Huseyin; Unlu, Ercument; Temizoez, Osman; Genchellac, Hakan[Abstract Not Available]Öğe Hepatic pseudolesion around the falciform ligament: Prevalence, aberrant venous supply, and fatty infiltration evaluated by multidetector computed tomography and magnetic resonance imaging(Lippincott Williams & Wilkins, 2007) Genchellac, Hakan; Yilmaz, Sabri; Ucar, Adem; Dursun, Memduh; Demir, Mustafa Kemal; Yekeler, EnsarPurpose: The aim of this study was to determine the prevalence and aberrant venous supply (inferior veins of Sappey) of hypoattenuating hepatic pseudolesions seen around the falciform ligament on portal-dominant phase multidetector computed tomography (MDCT) and the frequency of fatty infiltration of these pseudolesions on chemical-shift magnetic resonance imaging. Materials and Methods: Portal-dominant phase abdominal MDCT examinations of 728 patients were evaluated for the presence of a pseudolesion around the falciform ligament, and those with a presumed pseudolesion underwent chemical-shift magnetic resonance imaging to detect the fatty infiltration. Reconstructed MDCT images were investigated for the presence of an inferior vein of Sappey, and 30 patients without a pseudolesion were evaluated as a control group. Results: A total of 160 pseudolesions Were detected around the falciform ligament in 146 (20%) patients. The longest diameter of the pseudolesions was in the craniocaudal direction in most patients (61%). An inferior vein of Sappey supplying these pseudolesions was depicted in 40 (27%) patients, and it was highly significant (P = 0.001) compared with the controls for the presence of a pseudolesion around the falciform ligament. Fatty infiltration was found in 47 (29%) patients. Conclusions: Hepatic pseudolesions around the falciform ligament are frequently encountered on portal-dominant phase MDCT images. Detection of craniocaudal extension, inferior veins of Sappey, and fatty infiltration of these pseudolesions, which were firstly described in this article, with the largest subject group based on cross-sectional imaging, might be valuable in excluding true tumors.Öğe Herlyn-Werner-Wunderlich syndrome: a rare cause of infertility (2009: 2b)(Springer, 2009) Sarac, Armagan; Demir, Mustafa KemalUterus didelphys with obstructed hemivagina and ipsilateral renal agenesis is a rare and specific entity referred to as Herlyn-Werner-Wunderlich syndrome. It usually presents after menarche with remittent pelvic pain and a palpable pelvic mass due to hematocolpos. It rarely presents with primary infertility in early adulthood. In this report, a case of Herlyn-Werner-Wunderlich syndrome with primary infertility in a young woman is described with MR imaging findings.Öğe Hypothenar hammer syndrome(John Wiley & Sons Inc, 2008) Genchellac, Hakan; Demir, Mustafa Kemal; Unlu, Ercuement; Temizoz, Osman; Ozdemir, HuseyinWe report a case of hypothenar hammer syndrome following a single severe blunt trauma in a 24-year-old man with a painful pulsatile mass, numbness in the fourth and fifth fingers, and intolerance to cold. The gray-scale and color Doppler sonographic findings are presented with correlation with MRI. (C) 2007 Wiley Periodicals, Inc.Öğe Incidental Pancreatic Lipomas: Computed Tomography Imaging Findings with Emphasis on Diagnostic Challenges(Elsevier Science Bv, 2010) Temizoz, Osman; Genchellac, Hakan; Unlu, Ercument; Kantarci, Fatih; Umit, Hasan; Demir, Mustafa KemalPurpose: The purpose of this study was to describe the computed tomography (CT) findings of pancreatic lipomas of 9 cases, with emphasis to diagnostic challenges. Methods: Between March 2006 and April 2008, 9 patients with pancreatic lipomas that were diagnosed by CT were reviewed in the present study. Clinical data and CT features of these 9 cases were retrospectively analysed. The patient population included 5 men and 4 women, aged 42-81 years (mean age, 65.8 years). The patients were followed up for at least 2 years with control CTs. Results: In all 9 cases, a well-bordered nodular fat density lesion was incidentally detected in the pancreas. Four of the lesions had a lobulated contour, and 2 of them had septations. Two of the lipomas were located in the head, 3 in the neck, 3 in the corpus, and 1 in the tail. The CT densitometric values were between -90 and -120 HU, with a mean value of 106 HU. No pancreatic or biliary dilatation or compression to the adjacent structures was seen. All the cases had control CTs, and the lipomas remained unchanged during the follow-up period. Histopathologic confirmation of the diagnosis was not planned for the cases. Conclusion: Lipomas are rarely encountered in the pancreas. They often are diagnosed coincidentally as small, well-circumscribed, encapsulated, homogeneous, mature adipose masses on imaging studies. Imaging follow-up strategy or histopathologic confirmation is not necessary in asymptomatic patients.Öğe Perineal angiomyxomas: Can a differential diagnosis be made with imaging studies?(Radiological Soc North America (Rsna), 2007) Demir, Mustafa Kemal; Genchellac, Hakan; Ozdemir, Huseyin[Abstract Not Available]Öğe Phase inversion harmonic imaging improves assessment of renal calculi(John Wiley & Sons Inc, 2008) Ozdemir, Huseyin; Demir, Mustafa Kemal; Temizoz, Osman; Genchellac, Hakan; Unlu, ErcumentPurpose. To compare phase inversion harmonic imaging (PIHI) with fundamental imaging (FI) in the evaluation of renal calculi. Methods. Thirty adult patients with renal calculi (17 men, 13 women; mean age 44 years [range, 25-71]) underwent transabdominal sonographic examination of the urinary system. Both kidneys and renal calculi were examined with PIHI and A. Overall renal con picuity, calculus visibility, and clarity of posterior shadowing were assessed subjectively using a 4-point scale (0 being the worst, 3 being the best). The maximum diameter of the calculi was measured using both techniques. The effect of body mass index on qualitative scoring and quantitative measurements was evaluated. Results. PIN improved overall renal conspicuity compared with A (p < 0.001). The visibility of the calculi and clarity of posterior shadowing were significantly better with PIHI than with A (p, < 0.001 for both parameters). The maximum diameter of calculi was larger with PIHI than with FI (p < 0.001). The superiority of PIHI over FI regarding overall conspicuity of the kidney, visibility of the calculus, and clarity of posterior shadowing scores increased in the obese group (p < 0.001 for all 3 parameters). The mean calculus diameter difference between the 2 techniques was significantly higher in the obese group. Conclusion. The routine use of PIHI is recommended in the evaluation of renal calculi. (c) 2007 Wiley Periodicals, Inc.Öğe Single voxel proton MR spectroscopy findings of typical and atypical intracranial meningiomas(Elsevier Ireland Ltd, 2006) Demir, Mustafa Kemal; Iplikcioglu, A. Celal; Dincer, Alp; Arslan, Mahmut; Sav, AydinPurpose: To prospectively define proton magnetic resonance spectroscopy (MRS) findings of meningiomas, and describe the ability or inability of short- and long-echo MRS to differentiate typical and atypical meningiomas in vivo. Material and methods: Seventeen patients with pathologically confirmed typical meningiomas and six with atypical meningiomas were evaluated with conventional MR imaging and MRS before resection. MRS studies using point-resolved spectroscopy (PRESS) localisation, at short- and long-echo time (TR 2000 ms, TE: 30 and 144 ms, 64-96 acquisition) were acquired on a 1.5 T scanner. MRS data obtained from these patients were compared with histopathological findings. Mean cellular proliferation (MIB-1) antibody staining against the Ki-67 antigen was also determined in all meningiomas. Results: Prominent choline (Cho) was present in all meningiomas. Alanine (Ala) was observed in 21 cases of the 23 meningiomas. Acetylaspartate (NAA) and creatine (Cr) were either not observed or detected in minimal amounts in at all both groups of meningiomas on long TE (144 ms) spectra. The mean Cho/Cr values in the four atypical meningiomas were 4.44 +/- 0.30 (mean standard deviation) and 3.39 +/- 0.52 in the 12 typical meningiomas on short TE spectra. Cho/Cr ratio could not be determined in the other seven cases because of a lack of creatine peak. Of the five meningiomas in which a lactate peak was detected, four were in typical cases and only one was in atypical meningioma. Mean MIB-1 proliferation index was 3.7% in typical meningiomas and 10% in atypical meningiomas. Conclusion: Prominent Cho, absence or low amount of NAA and Cr, and presence of Ala were common characteristics of spectral pattern of both atypical and typical meningiomas on MRS. MRS cannot reliably differentiate typical intracranial meningiomas from atypical meningiomas preoperatively. Mean MIB-1 proliferation index was well correlated with histopathology findings. (C) 2006 Elsevier Ireland Ltd. All rights reserved.Öğe Tentorial haematoma in a newborn(Springer, 2009) Demir, Mustafa Kemal; Unlu, Ercument[Abstract Not Available]Öğe Unusual appearance of lumbar facet synovial cyst and differential diagnosis(Radiological Soc North America, 2007) Demir, Mustafa Kemal[Abstract Not Available]Öğe Unusual cause of persistent abdominal pain in a young girl(Springer, 2007) Demir, Mustafa KemalA solid-pseudopapillary tumour, a rare disease of the pancreas, in a young woman is presented. Since treatment involves complete excision of the mass, an early diagnosis is crucial to allow the curative resection.Öğe Value of Dynamic Contrast-Enhanced MRI and Correlation with Tumor Angiogenesis in Bladder Cancer(Amer Roentgen Ray Soc, 2009) Tuncbilek, Nermin; Kaplan, Mustafa; Altaner, Semsi; Atakan, Irfan H.; Sut, Necdet; Inci, Osman; Demir, Mustafa KemalOBJECTIVE. The aim of this study was to investigate dynamic contrast-enhanced MRI (DCE-MRI) for the noninvasive measurement of bladder cancer angiogenesis by correlation with microvessel density, histologic grade, and tumor staging, and to predict the outcome of local recurrence. MATERIALS AND METHODS. Twenty-four patients with bladder cancer were examined using DCE-MRI. Hemodynamic parameters obtained by DCE-MRI included peak time enhancement in the first minute (E-max/1) after contrast administration, second minute (E-max/2), third minute (E-max/3), fourth minute (E (max/4)), and fifth minute (E-max/5), and the steepest slope. Microvessel density was identified by immunostaining of endothelial cells using FVIII-related antigen. The Mann-Whitney U test, multivariate discriminant analysis, Spearman's correlation coefficient, and analysis of variance were used for statistical analysis. RESULTS. Correlation was seen between DCE-MRI parameters (E-max/1 and steepest slope) and microvessel density (p<0.05). E-max/1 and steepest slope were found to have a statistically significant correlation with histologic grade (p<0.05 and p<0.01, respectively). A significant difference was seen between groups of patients with and without local recurrence with regard to two of the DCE-MRI parameters (p<0.05 for E-max/1 and E-max/2). CONCLUSION. The contrast enhancement patterns on DCE-MRI are influenced by tumor angiogenesis, as reflected by elevated microvessel density expression. Therefore, they are valuable indicators for assessing tumor angiogenic activity and tumor neovascularization in bladder cancers.
