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Öğe Churg-Strauss syndrome associated with montelukast(Turkish Assoc Tuberculosis & Thorax, 2008) Ozlen, Burcu; Ozdemir, Levent; Eskitutuncu, Banu; Cevirme, Leyla; Kurtar, Nazan; Soy, Mehmet; Hatipoglu, Osman NuriA 47 year old woman who had a history of asthma for 15 years referred to our hospital because of infiltrates on her chest radiograph that not responded to antibiotic treatment. We found that she had eosinophilia in peripheral blood (38%) and bronchoalveolar lavage (54%), nasal polyposis, and transient pulmonary infiltrates, and in the base of these findings we diagnosed as Churg-Strauss Syndrome (CSS). She has been using montelukast for 2 years. By examining her previous medical records, we observed that while eosinophil rates in peripheral blood were normal before montelukast usage, after this therapy eosinophil rates were greater 10 percent. Therefore, we thought that CSS was to be associated with montelukast usage. After just montelukast therapy was discontinued, clinical and radyographic parameters and the eosinophil counts (20%) improved. We present this case of CSS associated with montelukast in whom spontaneous remission was observed without using corticosteroids and cytotoxic agents.Öğe Mortality Rates and Related Factors in Respiratory Intensive Care Unit Patients(Aves, 2007) Altiay, Gundeniz; Tabakoglu, Erhan; Ozdemir, Levent; Tokuc, Burcu; Cevirme, Leyla; Hatipoglu, Osman Nuri; Caglar, TuncayThe aim of this study is to identify the mortality rates and the influential factors in the respiratory intensive care unit (ICU). We prospectively evaluated a total of 150 patients consecutively admitted with respiratory failure between May 2003 and May 2005 in Trakya University Hospital, and 135 patients were enrolled in the study. The patients excluded from the study were the ones who died within the first 24 hours of ICU (n: 8), or had malignant diseases (n: 7). Chi-square test and t-test were used to compare hospital survivors with non-survivors, and logistic regression analysis was performed to define independent factors influencing the mortality rates in the hospital. To determine the efficiency of APACHE II, ROC analysis was used. 92 of the patients were male and 43 were female. The mean age was 64.9 +/- 12.9 years. The mortality rate was 32.6% (n: 44). The highest mortality rate was in patients with severe pneumonia/sepsis. (54.2%). The main conditions independently associated with increased mortality rate were arrhythmias (odds ratio [OR], 8.10; 95% confidence interval [CI], 2.67-24.58; p < 0.05), the need for invasive mechanical ventilation (OR, 6.04; 95% CI, 1.88 - 19.34; p < 0.05), the need for cardiotonic medication (OR: 5.36; % 95 CI: 1.67 - 17.22, p<0.05) and ventilator-associated pneumonia (OR: 5-21; 95% CI: 1.54-17.63; p < 0.05).Öğe Treatment of a primary pulmonary alveolar proteinosis case with severe hypoxaemia by using segmental lavage technique(Acad Medicine Singapore, 2007) Edis, Ebru Cakir; Tabakoglu, Erhan; Caglar, Tuncay; Hatipoglu, Osman Nuri; Cevirme, Leyla; Alagol, Aysin[Abstract Not Available]
