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Öğe Case Report of An Incidental Unicentric Castleman Disease(Trakya Üniversitesi, 2021) Cengiz, Elif; Certel, Alperen Taha; Ayrık, Mert Yücel; Arıkan, Mehmet Gürkan; Mercan, Elif; Öz Puyan, Fulya; Atakan, İrfan HüseyinAims: To emphasize the hardship of diagnosing Castleman disease and present a potential treatment method. Case Report: A sixty-three-year-old male patient was admitted to the outpatient clinic with an attack of acute cholecystitis. The patient’s abdominal computed tomography revealed an incidentally detected lipid dense solid mass (64x53x37 mm) at the level of right renal hilum with 29x13 mm solid components in the middle. The patient was admitted to the urology department and underwent surgery where the mass was totally excised due to suspicion of a malignancy (liposarcoma). Histopathological examination later on resulted with unicentric Castleman disease, hyaline vascular subtype. Conclusion: Since unicentric Castleman disease has an asymptomatic clinical course and is quite rare, it is necessary to rule out many potential possibilities before reaching a proper diagnosis. However, unicentric Castleman disease usually exhibits a good prognosis after the removal of the affected lymph node. Still, Castleman disease should be a candidate considered in the differential diagnosis of patients with incidentally discovered lymphadenopathy. On the whole, for a better understanding of underlying pathophysiology, there still lies a gap to be filled with knowledge acquired through further studies.Öğe The Impact of Open Inguinal Hernia Mesh Repair on Quality of Life(Trakya Üniversitesi, 2020) Cengiz, Elif; Aksu, Toprak Kağan; Çifcibaşı, Hilal Sena; Demirel, TuğrulAims: This study aims to evaluate the effect of open inguinal hernia repair with mesh on the quality of life of the patients whowere operated at a university hospital. Methods: In this cohort study, 86 patients who had undergone an open inguinal herniarepair at General Surgery Department in a university hospital between January 2017 and October 2019 were asked to fill out theCarolinas Comfort Scale questionnaire and the data were analyzed retrospectively. Results: The total number of patients in thestudy was 86. Seventy-three were male (84%) and 13 were female (16%). The median age was 53 years ranging from 18 to 82. Thedifference of pre- and post-operative scores revealed high significance in all categories and in total; laying down, bending over,sitting up, performing activities of daily life, coughing or deep breathing, walking or standing, walking up or down the stairs,exercising and total score. Conclusion: Inguinal hernia decreases the quality of daily life by limiting the movements with groinpain. Surgical low-tension repair with mesh improves the quality of life significantly. Keywords: Inguinal hernia, quality of life,mesh repairÖğe Length of Hospital Stays of Patients Operated Due to Glioma Tumours in Neurosurgery Clinics and Intensive Care Units(Trakya Üniversitesi, 2021) Özyiğit, Irmak; Akay, Fatih Erkan; Cengiz, Elif; Özdemir, Janset; Tuncer, Pınar; Şenödeyici, Eylül; Kızılkaya, SarperAims: To evaluate the relationship between the length of hospital stay and age, gender, and disease characteristics among glioma patients who went under surgery in Trakya University School of Medicine. Methods: The data of 51 glioma patients over 18 years of age, who have been followed up during 2019-2020 in Trakya University School of Medicine, Department of Neurosurgery were analyzed. Patients' data comprised of sex, age, tumour location, grades of the tu- mours, the presence of isocitrate dehydrogenase mutation, whether the patients were hospitalized in the intensive care unit or the neurosurgery clinic, duration of hospitalization, and whether radiotherapy and chemotherapy was received. Length of hospital stay was evaluated separately as intensive care unit and the neurosurgery clinic. Results: Out of 51 patients diagnosed with glioma, 18 (35.3%) were female, and 33 (64.7%) were male. The length of neurosurgery clinic and intensive care unit stays were not associated with radiotherapy and chemotherapy approaches. There was a statistically significant difference between the male and female patients in terms of the number of days stayed in the neurosurgery clinic. Conclusion: In conclusion, gender affected the length of neurosurgery clinic stays with a longer duration for female patients in our clinic. A waste number of parameters, including social ones, affect hospital stays. To reveal predictors of postoperative hospitalization thoroughly and overcome the study’s limitations, further prospective studies with larger sample sizes are needed.Öğe Partial Nephrectomy of a Horseshoe Kidney With Renal-Cell Carcinoma and Cholecystectomy: a Case Report(Trakya Üniversitesi, 2020) Cengiz, Elif; Şişman, Fevzi Oktay; Koçyiğit, Beliz; Arıkan, Mehmet Gürkan; Aktoz, TevfikAims: Horseshoe kidneys are the most common type of renal fusion anomaly and it may be associated with other anomalies and complications. Our case aims to present the partial nephrectomy of a horseshoe kidney with renal-cell carcinoma and cholecystectomy. Case Report: A sixty-year-old male patient was admitted to our outpatient clinic with a 3 cm suspicious mass in the horseshoe kidney that was detected during an attack of acute cholecystitis. Computed tomography revealed a heteroge- neous hypodense lesion containing millimetric calcific foci of 35x31x33 mm in size at the ventral middle part of the right kid- ney. Partial nephrectomy was performed non-ischemically and then cholecystectomy was performed. Pathological examination revealed stage T1a clear cell renal carcinoma, WHO/ISUP Grade 2 with a negative surgical margin. During follow-up; urea, creatinine, and glomerular filtration rate were found to be normal. Conclusion: Horseshoe kidneys are fairly common among renal anomalies. Cholecystectomy following non-ischemic partial nephrectomy for a tumor in the horseshoe kidney is a rare case.Öğe Retrospective Analysis of Follicular Lymphoma Patients in Trakya University School of Medicine: a Single Center Experience(Trakya Üniversitesi, 2021) Akay, Fatih Erkan; Koçyiğit, Beliz; Şişman, Fevzi Oktay; Ayrık, Mert Yücel; Savaşır, İpek; Cengiz, Elif; Demirci, UfukAims: To establish a dataset including demographic features, disease characteristics, and survival rate of follicular lymphoma patients in Trakya Universi- ty School of Medicine and contribute to the database of follicular lymphoma in Turkey. Methods: In this retrospective cross-sectional study, we analyzed data constituting of follicular lymphoma patients over 18 years of age followed during the years of 2015-2020 in Trakya University Division of Hematology. Results: Out of 43 patients, 22 (51.2%) were female and 21 (48.8%) were male. The mean age was 56.56 (standard deviation 13.24) years. There were 5 (11.6%) pa- tients with B symptoms, presence of bone marrow involvement was seen in 17 (39.5%) patients, lastly, there were 18 (41.9%) patients with splenomegaly. Twen- ty-one (48.8%) patients received rituximab, cyclophosphamide, doxorubicin hydrochloride, vincristine sulfate, and prednisone, making it the most common treatment protocol administered in our study. Conclusion: Follicular lymphoma patients usually end up getting diagnosed at an advanced stage of the disease, presenting with incidentally noticed painless lymphadenopathy. Additionally, based on evidence in the literature, a clear gap in the successful diagnosis of follic- ular lymphoma patients can be observed between developed and developing countries. To overcome this hurdle, enhanced cooperation with hematopathology may lead to an increased awareness enabling physicians to make a more accurate diagnosis. Nonetheless, further studies are still needed to fully apprehend the epidemiology of follicular lymphoma patients in Turkey.Öğe Squamous Cell Carcinoma of the Caudal Nasal Septum and the Nasal Vestibule: a Case Report(Trakya Üniversitesi, 2021) Tan, Berfin; Cengiz, Elif; Kurtoğlu, Berra; Çalışkan, Elif; Kef, KemalAims: The nasal septum is an unusual place for malignant tumors to occur. The condition may be accompanied by non-specific symptoms that may cause delays in seeking medical care or may misguide the physician due to the condition’s rarity. We hereby aim to present a rare case of a squamous cell carcinoma in a 65-year-old male patient with recently progressing symptoms. Case Report: A 65-year-old male patient was admitted to Private Keşan Hospital’s Ear- Nose-Throat Department with swelling and wounds in the nose, and inability to breathe complaints. After the biopsy, pathological examination revealed moderately differentiated squamous cell carcinoma. The patient was operated with success; the mass was thoroughly dissected and a full-thickness skin graft from the left supraclavicular region was used in the reconstruction of defected areas. Recovery was uneventful due to early diagnosis and admission, with no relapse or cosmetic concern during monthly visits in the following years. Conclusion: As seen in this case, full-thickness skin grafts can be successfully used in intranasal and extranasal reconstructions, provided that they are obtained from areas with appropriate thickness. Early diagnosis and frequent monitoring are crucial in patients with squamous cell carcinoma since these tumors respond exceptionally well to treatment; although the recurrence rate is remarkably high.
