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Öğe A Case of Autoimmune Encephalitis with Refractory Status Epilepticus(Kare Publ, 2019) Cakar, Merve Melodi; Aksar, Aslihan; Akpinar, Meliha; Mercan, Elif; Kehaya, Sezgin; Guldiken, BaburhanRefractory status epilepticus is usually caused by a severe brain injury and has a high rate of mortality and morbidity despite the infusion of antiepileptic drugs and anesthetic agents. Autoimmune encephalitis is one cause of refractory status epilepticus and status epilepticus may be the initial symptom. The seizures are generally resistant to standard treatment and may require immunotherapeutics. This is a description of a patient who had refractory status epilepticus despite appropriate doses of antiepileptic and general anesthetic drugs, but responded to intravenous immunoglobulin therapy. Examinations revealed an ovarian teratoma with a negative serum N-methyl-D-aspartate receptor antibody.Öğe Factors affecting long-term prognosis in adult patients with psychogenic non-epileptic seizures(Literatura Medica, 2024) Turksever, Meliha; Guldiken, Baburhan; Ozkan, Hulya; Cakar, Merve MelodiBackground and purpose - Among epileptic patients who are monitored using the video-electroencephalography monitoring (VEM) technique, in some patients a psychogenic non-epileptic seizure (PNES) can be identified as a definitive diagnosis. The long-term prognosis of these patients is not well known. In this study, we aimed to determine the factors that affect the prognosis of PNES. Methods - Forty-one PNES patients diagnosed using VEM between 2012 and 2022 were questioned about their PNES frequencies in the last 12 months. According to their semiological characteristics, PNES types were divided into motor and non-motor seizures. The effects of clinical characteristics (e.g. age, gender, marital status, education level and PNES type) on the prognoses were identified. Results - Twenty-one PNES patients (51.2%) had long-term seizure freedom after VEM. Thirteen of them (31.7%) entered the seizure-free period immediately after VEM, and the other eight (19.5%) continued suffering from PNES for several years and became seizure free in the last 12 months. In the poor-prognosis group, female cases showed worse prognoses than male cases. The prognoses of motor and non-motor PNES types did not show significant differences. Conclusion - This study showed that 51.2% of the PNES patients examined had long-term seizure freedom and that female patients had worse prognoses than male patients.Öğe Late-Onset Generalized Myoclonic Seizure: Case Report(Kare Publ, 2021) Ozkan, Hulya; Guldiken, Baburhan; Cakar, Merve Melodi; Sunal, Asli Sert; Kehaya, SezginMost of the epileptic seizures that begin at an advanced age are focal onset seizures due to an underlying structural lesion. Generalized myoc-lonic seizures, usually seen in adolescence, are very rare in elderly patients without a history of epilepsy. In this study, we present a 60-year-old patient with generalized myoclonic seizures with electrophysiological findings. Because of the late-onset, myoclonic jerks were first evaluated with the diagnosis of non-epileptic psychogenic attack in an external health center. The patient was diagnosed with seizure recordings in Elec-troencephalography-video monitoring. The patient responded well to the antiepileptic treatment and became seizure-free.Öğe Lower Motor Syndrome Limited to the Upper Extremities with a Snake-eyes Appearance on the Cervical Cord(Wolters Kluwer Medknow Publications, 2023) Cakar, Merve Melodi; Durgan, Oguzhan; Baysal, Leyla[Abstract Not Available]Öğe Posterior Reversible Encephalopathy Syndrome in the Late Postpartum Period: A Case Report(Turkish Neurological Soc, 2018) Cakar, Merve Melodi; Kehaya, Sezgin; Ozkan, Hulya; Guldiken, Baburhan Feyzullah[Abstract Not Available]