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Öğe Case report: Subcutaneous metastasis from small cell carcinoma of the prostate(Springer, 2007) Kaplan, Mustafa; Atakan, Irfan H.; Bilgi, Selcuk; Inci, OsmanPure primary small cell carcinoma of the prostate (SCCP) is an extremely rare entity. Natural history of this tumor is similar to that of the bronchogenic small cell carcinoma. Several theories of histogenesis have been proposed. Most widely accepted view is that SCCP arises from pluripotent stem cells of the prostate, which have the ability to differentiate into either epithelial or neuroendocrine type carcinomas. SCCP has an aggressive course, and a majority of patients have distant metastasis at presentation. Since it is a rare entity, no standard treatment regimen has been established. A case of primary pure SCCP with multiple subcutaneous metastases is presented.Öğe The effects of N-acetylcysteine on intestinal ischemia/reperfusion injury in rats(Saudi Med J, 2009) Ayvaz, Suleyman; Aksu, Burhan; Inan, Mustafa; Uzun, Hafize; Aydin, Seval; Bilgi, Selcuk; Umit, Hasan C.Objectives: To evaluate the effects of N-acetylcysteine (NAC) on the injury of intestinal ischemia-reperfusion. Methods: Forty-eight Wistar-Albino rats were divided into 6 groups: as control, ischemia, ischemia-reperfusion, ischemia + N-acetylcysteine, ischemia-reperfusion + N-acerylcysteine (IRN), and reperfusion + N-acetylcysteine (RN). Histopathologic examination was performed to all groups. In the tissue and plasma, and erythrocyte samples, malondialdehyde, superoxide dismutase, glutathione, and nitric oxide (NO) levels were evaluated. The present study was carried out in Trakya and Istanbul University, Edirne, Turkey between December 2002 and July 2003. Results: The most severe histopathological damage was seen in the intestinal ischemia-reperfusion group, and this damage was observed to be reduced by NAC administration. Lowest plasma malondialdehyde levels were observed in RN group. The tissue glutathione levels were found to be higher in RN group than those in IRN group. Conclusion: It was found that administration of NAC has important effects on the injury of intestinal ischemia, as well as, reperfusion in rats. N-acerylcysteine administration causes an improvement in the histopathologic findings of ischemia/reperfusion damages. The N-acerylcysteine treatment protects the antioxidant enzymes in the tissue, plasma, and the erythrocytes, which are crucially important in the intestinal schemia/reperfusion injury in rats.Öğe Granulomatous hypophysitis: presentation and MRI appearance(Churchill Livingstone, 2006) Unlu, Ercument; Puyan, Fulya Oz; Bilgi, Selcuk; Hamamcioglu, M. KemalGranulomatous hypophysitis (GrHy) is a relatively rare inflammatory disease compared with lymphocytic hypophysitis. Only a few cases with magnetic resonance imaging (MRI) findings have been reported to date. We describe the MRI findings for two patients with GrHy with unusual histories and clinical outcomes. (c) 2006 Elsevier Ltd. All rights reserved.Öğe Invading basal cell carcinoma of the bone: Diagnosis and treatment approaches(W B Saunders Co-Elsevier Inc, 2006) Aygit, Cemal; Top, Husamettin; Bilgi, Selcuk; Ozbey, Baykurt[Abstract Not Available]Öğe Kikuchi-Fujimoto disease coexisted with Sjogren's syndrome(Springer, 2007) Soy, Mehmet; Peynirci, Hande; Bilgi, Selcuk; Adali, Mustafa Kemal; Guresci, ServetHere we described a case of primary Sjogren's syndrome that coexisted with Kikuchi-Fujimoto disease.
